ECHDC2 - enoyl-CoA hydratase domain containing 2 Gene
Species: Homo sapiens
About ECHDC2
This gene has 26 transcripts (splice variants), 203 orthologues and 13 paralogues. Ubiquitous expression in liver (RPKM 18.0), ovary (RPKM 13.9) and 25 other tissues.
Summary
Predicted to enable enoyl-CoA hydratase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be active in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
ECHDC2 Products (4)
| mRNA | Protein | Name |
|---|---|---|
| NM_001198961.2 | NP_001185890.1 | enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform 1 |
| NM_001198962.1 | NP_001185891.1 | enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform 3 |
| NM_001319958.2 | NP_001306887.1 | enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform 4 |
| NM_018281.4 | NP_060751.2 | enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform 2 |
ECHDC2 Protein Structure
ECH_1: Enoyl-CoA hydratase/isomerase (40 - 284)
- 0
- 100
- 200
- 292 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
enoyl-CoA hydratase domain-containing protein 2, mitochondrial |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| 3-Methylglutaconic Aciduria, Type I |
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Bos taurus | ECHDC2 | VGNC | VGNC:55168 |
| Felis catus | ECHDC2 | VGNC | VGNC:80192 |
| Mus musculus | ECHDC2 | MGD | MGI:1289238 |
| Macaca mulatta | ECHDC2 | VGNC | VGNC:81390 |
| Rattus norvegicus | ECHDC2 | RGD | RGD:1308525 |
| Others | ECHDC2 | NCBI |