IRGC - immunity related GTPase cinema Gene

Homo sapiens

Also known as IFGGE; IRGC1; Iigp5; CINEMA; R30953_1

Gene ID: 56269 | Gene type: protein coding

About IRGC

This gene has 2 transcripts (splice variants), 395 orthologues and 1 paralogue. Restricted expression toward testis (RPKM 28.8).

Summary

Predicted to enable GTPase activity. Predicted to be involved in cellular response to interferon-beta and defense response. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022]

IRGC Products(1)

mRNA	Protein	Name
NM_019612.4	NP_062558.1	interferon-inducible GTPase 5

IRGC Protein Structure

IIGP

0
100
200
300
400
463 a.a.

Protein Preferred Names

Protein Names

interferon-inducible GTPase 5

immunity-related GTPase cinema 1

Related Diseases

Diseases

Alias

Chronic Inflammatory Demyelinating Polyneuritis

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

Japanese Spotted Fever

Oriental Spotted Fever

Rickettsia Japonica Spotted Fever

Ureterolithiasis

Calculus Of Ureter	Ureteric Stone
Ureteral Calculi	Ureteric Calculus
Stone In The Ureter	Ureter Calculi
Ureteral Calculus Or Stone	Ureterolith
Ureterolithiasis Nos

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06914	IRGC Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	IRGC	RGD	RGD:1311107
Bos taurus	IRGC	VGNC	VGNC:30281
Mus musculus	IRGC	MGD	MGI:2685948

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