Apip - APAF1 interacting protein Gene

Also Known as APIP2; CGI-29; Mmrp19

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56369

Summary

Predicted to enable identical protein binding activity; methylthioribulose 1-phosphate dehydratase activity; and zinc ion binding activity. Involved in regulation of ERK1 and ERK2 cascade. Acts upstream of or within negative regulation of apoptotic process. Predicted to be active in cytoplasm. Orthologous to human APIP (APAF1 interacting protein). [provided by Alliance of Genome Resources, Apr 2022]

Apip Products (3)

mRNA Protein Name
NM_001355473.1 NP_001342402.1 methylthioribulose-1-phosphate dehydratase isoform 2
NM_001355474.1 NP_001342403.1 methylthioribulose-1-phosphate dehydratase isoform 3
NM_019735.4 NP_062709.3 methylthioribulose-1-phosphate dehydratase isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of apoptotic process IMP
IMP: Inferred from mutant phenotype
15262985 MGI
acts upstream of or within negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
15262985 MGI
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
17086211 MGI
involved in regulation of ERK1 and ERK2 cascade IMP
IMP: Inferred from mutant phenotype
17086211 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

methylthioribulose-1-phosphate dehydratase

  • MTRu-1-P dehydratase

  • monocyte macrophage 19

  • monocyte/macrophage protein 19

  • probable methylthioribulose-1-phosphate dehydratase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00820 APIP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20249 Apip Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26757 Apip Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Apip NCBI NCBI:51074