Cript - CXXC repeat containing interactor of PDZ3 domain Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 56725

Summary

Enables PDZ domain binding activity and microtubule binding activity. Involved in several processes, including cytoplasmic microtubule organization; protein localization to microtubule; and regulation of postsynaptic density protein 95 clustering. Located in dendrite; neuronal cell body; and postsynaptic density. Orthologous to human CRIPT (CXXC repeat containing interactor of PDZ3 domain). [provided by Alliance of Genome Resources, Apr 2022]

Cript Products (1)

mRNA Protein Name
NM_019907.1 NP_063972.1 cysteine-rich PDZ-binding protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables PDZ domain binding IDA
IDA: Inferred from direct assay
9581762 RGD
enables microtubule binding IMP
IMP: Inferred from mutant phenotype
10570482 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
9581762 RGD
Biological Process GO Annotation Evidence References Source
involved in cytoplasmic microtubule organization IDA
IDA: Inferred from direct assay
9581762 RGD
involved in protein localization to microtubule IMP
IMP: Inferred from mutant phenotype
10570482 RGD
involved in regulation of postsynaptic density assembly IDA
IDA: Inferred from direct assay
10570482 RGD
involved in regulation of postsynaptic density assembly IMP
IMP: Inferred from mutant phenotype
10570482 RGD
involved in regulation of postsynaptic density protein 95 clustering IMP
IMP: Inferred from mutant phenotype
10570482 RGD
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
9581762 RGD
located in dendritic shaft IDA
IDA: Inferred from direct assay
9581762 RGD
located in dendritic spine IDA
IDA: Inferred from direct assay
9581762 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
10570482 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
10570482 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
9581762 RGD
is active in postsynaptic density, intracellular component IDA
IDA: Inferred from direct assay
11160391 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cysteine-rich PDZ-binding protein

  • cysteine-rich interactor of PDZ three

  • cysteine-rich interactor of PDZ3

  • postsynaptic protein Cript

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03178 CRIPT Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17976 Cript Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24447 Cript Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cript NCBI NCBI:9419