AVEN - apoptosis and caspase activation inhibitor Gene

Also Known as PDCD12

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57099

About AVEN

Cytogenetic location: 15q14 Genomic coordinates (GRCh38): 15:33,851,781-34,075,325 (from NCBI)

This gene has 4 transcripts (splice variants) and 185 orthologues. Ubiquitous expression in testis (RPKM 1.9), placenta (RPKM 1.7) and 25 other tissues.

Summary

Involved in negative regulation of apoptotic process. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

AVEN Products (1)

mRNA Protein Name
NM_020371.3 NP_065104.1 cell death regulator Aven

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10949025 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of apoptotic process IDA
IDA: Inferred from direct assay
10949025 GOA
Cellular Component GO Annotation Evidence References Source
located in membrane IDA
IDA: Inferred from direct assay
10949025 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cell death regulator Aven

  • apoptosis, caspase activation inhibitor

AVEN Antibodies

Cat. No. Product Name Application Reactivity
HY-P82474 AVEN Antibody (YA2219) WB, IHC-P Human, Mouse, Rat
HY-P82474A AVEN Antibody (YA2219)(PBS only) WB, IHC-P Human, Mouse, Rat

Related Diseases

Diseases Alias
Dyskeratosis Congenita, Autosomal Recessive 5

  • Dyskeratosis Congenita, Autosomal Dominant, 4

  • DKCB5

  • Autosomal Dominant Dyskeratosis Congenita 4

  • DKCA4

  • Autosomal Recessive Dyskeratosis Congenita 5

  • Dyskeratosis Congenita, Autosomal Recessive, 5

  • Dyskeratosis Congenita, Autosomal Dominant 4

  • Dyskeratosis Congenita, Autosomal Recessive, Type 5
Schizoid Personality Disorder
Voyeurism
Chromosome 15q13.3 Deletion Syndrome

  • Chromosome 15q13.3 Microdeletion Syndrome

  • 15q13.3 Microdeletion Syndrome

  • 15q13.3 Microdeletion

  • Microdeletion 15q13.3 Syndrome

  • Del(15)(Q13.3)

  • Monosomy 15q13.3
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-126166 NOC-5 Activator 98.50% Unkown
HY-RS01277 AVEN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17945 Aven Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24416 Aven Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus AVEN MGD MGI:1921518
Bos taurus AVEN VGNC VGNC:26353
Felis catus AVEN VGNC VGNC:60047
Rattus norvegicus AVEN RGD RGD:1309928
Macaca mulatta AVEN VGNC VGNC:70059
Others AVEN NCBI