AVEN - apoptosis and caspase activation inhibitor Gene

Homo sapiens

Also known as PDCD12

Gene ID: 57099 | Gene type: protein coding

About AVEN

Cytogenetic location: 15q14 Genomic coordinates (GRCh38): 15:33,851,781-34,075,325 (from NCBI)

This gene has 4 transcripts (splice variants) and 185 orthologues. Ubiquitous expression in testis (RPKM 1.9), placenta (RPKM 1.7) and 25 other tissues.

Summary

Involved in negative regulation of apoptotic process. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

AVEN Products(1)

mRNA	Protein	Name
NM_020371.3	NP_065104.1	cell death regulator Aven

Protein Preferred Names

Protein Names

cell death regulator Aven

apoptosis, caspase activation inhibitor

Related Diseases

Diseases

Alias

Dyskeratosis Congenita, Autosomal Recessive 5

Dyskeratosis Congenita, Autosomal Dominant, 4	DKCB5
Autosomal Dominant Dyskeratosis Congenita 4	DKCA4
Autosomal Recessive Dyskeratosis Congenita 5	Dyskeratosis Congenita, Autosomal Recessive, 5
Dyskeratosis Congenita, Autosomal Dominant 4	Dyskeratosis Congenita, Autosomal Recessive, Type 5

Schizoid Personality Disorder

Voyeurism

Chromosome 15q13.3 Deletion Syndrome

Chromosome 15q13.3 Microdeletion Syndrome	15q13.3 Microdeletion Syndrome
15q13.3 Microdeletion	Microdeletion 15q13.3 Syndrome
Del(15)(Q13.3)	Monosomy 15q13.3

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01277	AVEN Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	AVEN	MGD	MGI:1921518
Bos taurus	AVEN	VGNC	VGNC:26353
Felis catus	AVEN	VGNC	VGNC:60047
Rattus norvegicus	AVEN	RGD	RGD:1309928
Macaca mulatta	AVEN	VGNC	VGNC:70059
Others	AVEN	NCBI