NDRG3 - NDRG family member 3 Gene

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 57446

About NDRG3

Cytogenetic location: 20q11.23 Genomic coordinates (GRCh38): 20:36,651,771-36,746,090 (from NCBI)

This gene has 5 transcripts (splice variants), 294 orthologues and 3 paralogues. Ubiquitous expression in brain (RPKM 38.0), prostate (RPKM 20.1) and 23 other tissues.

Summary

Predicted to be involved in signal transduction. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

NDRG3 Products (2)

mRNA	Protein	Name
NM_022477.4	NP_071922.2	protein NDRG3 isoform b
NM_032013.4	NP_114402.1	protein NDRG3 isoform a

Gene Ontology

Cellular Component

Cellular Component GO Annotation	Evidence	References	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	11936845	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NDRG3 Protein Structure

Ndr

0
100
200
300
375 a.a.

Protein Preferred Names	Protein Names
protein NDRG3	N-myc downstream-regulated gene 3 protein

NDRG3 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P86982	NDRG3 Antibody (YA6675)	WB, IHC-P, FC	Human, Mouse, Rat

Related Diseases

Diseases	Alias
Charcot-Marie-Tooth Disease, Type 4d	Charcot-Marie-Tooth Disease Type 4d CMT4D Hmsnl Hmsn4d Charcot-Marie-Tooth Neuropathy Type 4d Hereditary Motor And Sensory Neuropathy Lom Type Hmsn-Lom Neuropathy, Hereditary Motor And Sensory, Lom Type Charcot-Marie-Tooth Disease, Demyelinating, Autosomal Recessive, Type 4d Charcot-Marie-Tooth Neuropathy, Type 4d Autosomal Recessive Demyelinating Charcot-Marie-Tooth Disease Type 4d Hmsn Lom Type Hmsn, Lom Type Hereditary Motor And Sensory Neuropathy, Lom Type Charcot-Marie-Tooth Disease 4d Charcot-Marie-Tooth Disease Demyelinating Autosomal Recessive 4d Hereditary Motor And Sensory Neuropathy Ivd Hmsn Ivd
Erythrocytosis, Familial, 3	ECYT3 Familial Erythrocytosis 3 Erythrocytosis, Familial, Type 3
Transitional Papilloma	Transitional Cell Papilloma Transitional Cell Papilloma, Benign

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09116	NDRG3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS22673	Ndrg3 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS29187	Ndrg3 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	NDRG3	MGD	MGI:1352499
Canis familiaris	NDRG3	VGNC	VGNC:43680
Rattus norvegicus	NDRG3	RGD	RGD:1359424
Macaca mulatta	NDRG3	VGNC	VGNC:74954
Bos taurus	NDRG3	VGNC	VGNC:31940
Felis catus	NDRG3	VGNC	VGNC:81130