Cdon - cell adhesion molecule-related/down-regulated by oncogenes Gene

Also Known as CDO; Cd0; Orcam

Species: Mus musculus

Gene Type: protein coding
Gene ID: 57810

Summary

Acts upstream of or within several processes, including animal organ development; positive regulation of intracellular signal transduction; and positive regulation of nitrogen compound metabolic process. Predicted to be located in cell surface. Predicted to be integral component of plasma membrane. Is expressed in several structures, including central nervous system; embryo mesenchyme; genitourinary system; limb bud; and sensory organ. Used to study holoprosencephaly 11. Human ortholog(s) of this gene implicated in holoprosencephaly 11. Orthologous to human CDON (cell adhesion associated, oncogene regulated). [provided by Alliance of Genome Resources, Apr 2022]

Cdon Products (7)

mRNA Protein Name
NM_001405246.1 NP_001392175.1 cell adhesion molecule-related/down-regulated by oncogenes precursor
NM_001405247.1 NP_001392176.1 cell adhesion molecule-related/down-regulated by oncogenes precursor
NM_001405248.1 NP_001392177.1 cell adhesion molecule-related/down-regulated by oncogenes precursor
NM_001405249.1 NP_001392178.1 cell adhesion molecule-related/down-regulated by oncogenes precursor
NM_001405250.1 NP_001392179.1 cell adhesion molecule-related/down-regulated by oncogenes precursor
NM_001405251.1 NP_001392180.1 cell adhesion molecule-related/down-regulated by oncogenes precursor
NM_021339.3 NP_067314.2 cell adhesion molecule-related/down-regulated by oncogenes precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11782431 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within anterior/posterior pattern specification IMP
IMP: Inferred from mutant phenotype
19754878 MGI
acts upstream of or within cell fate specification IGI
IGI: Inferred from genetic interaction
16647304 MGI
acts upstream of or within cerebral cortex development IMP
IMP: Inferred from mutant phenotype
16648472 MGI
acts upstream of or within embryonic body morphogenesis IGI
IGI: Inferred from genetic interaction
16647304 MGI
acts upstream of or within embryonic body morphogenesis IMP
IMP: Inferred from mutant phenotype
16647303 MGI
acts upstream of or within embryonic morphogenesis IGI
IGI: Inferred from genetic interaction
17504941 MGI
acts upstream of or within embryonic retina morphogenesis in camera-type eye IMP
IMP: Inferred from mutant phenotype
19754878 MGI
acts upstream of or within lens development in camera-type eye IMP
IMP: Inferred from mutant phenotype
19754878 MGI
acts upstream of or within myoblast fusion IMP
IMP: Inferred from mutant phenotype
15520228 MGI
acts upstream of neural precursor cell proliferation IMP
IMP: Inferred from mutant phenotype
16648472 MGI
acts upstream of neuroblast proliferation IMP
IMP: Inferred from mutant phenotype
16648472 MGI
acts upstream of neuron differentiation IMP
IMP: Inferred from mutant phenotype
19244314 MGI
acts upstream of or within positive regulation of MAPK cascade IGI
IGI: Inferred from genetic interaction
20160094 MGI
acts upstream of or within positive regulation of MAPK cascade IMP
IMP: Inferred from mutant phenotype
19244314 MGI
acts upstream of or within positive regulation of neuroblast proliferation IMP
IMP: Inferred from mutant phenotype
16648472 MGI
acts upstream of or within positive regulation of neuron differentiation IDA
IDA: Inferred from direct assay
16648472 MGI
acts upstream of or within positive regulation of neuron differentiation IMP
IMP: Inferred from mutant phenotype
16648472 MGI
acts upstream of or within positive regulation of protein phosphorylation IDA
IDA: Inferred from direct assay
15572127 MGI
acts upstream of or within positive regulation of skeletal muscle tissue development IMP
IMP: Inferred from mutant phenotype
15572127 MGI
acts upstream of or within positive regulation of small GTPase mediated signal transduction IMP
IMP: Inferred from mutant phenotype
19244314 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
15572127 MGI
acts upstream of protein phosphorylation IDA
IDA: Inferred from direct assay
15572127 MGI
acts upstream of or within regulation of neuron differentiation IMP
IMP: Inferred from mutant phenotype
16648472 MGI
acts upstream of or within regulation of protein binding IDA
IDA: Inferred from direct assay
15572127 MGI
acts upstream of or within skeletal muscle satellite cell differentiation IMP
IMP: Inferred from mutant phenotype
15572127 MGI
acts upstream of skeletal muscle tissue development IMP
IMP: Inferred from mutant phenotype
15572127 MGI
acts upstream of or within smoothened signaling pathway IGI
IGI: Inferred from genetic interaction
16647304 MGI
acts upstream of or within striated muscle cell differentiation IGI
IGI: Inferred from genetic interaction
20160094 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cell adhesion molecule-related/down-regulated by oncogenes

  • CAM-related/down-regulated by oncogenes

  • immunoglobulin superfamily member CDO

  • oncogene-regulated cell adhesion molecule

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02422 CDON Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19882 Cdon Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26381 Cdon Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdon NCBI NCBI:50937