SDF2 - stromal cell derived factor 2 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 6388

About SDF2

Cytogenetic location: 17q11.2 Genomic coordinates (GRCh38): 17:28,648,346-28,662,194 (from NCBI)

This gene has 10 transcripts (splice variants), 196 orthologues and 3 paralogues. Ubiquitous expression in adrenal (RPKM 19.5), placenta (RPKM 16.0) and 25 other tissues.

Summary

The protein encoded by this gene is believed to be a secretory protein. It has regions of similarity to hydrophilic segments of yeast mannosyltransferases. Its expression is ubiquitous and the gene appears to be relatively conserved among mammals. Alternate splicing results in both coding and non-coding variants. A pseudogene of this gene is located on chromosome 15. [provided by RefSeq, Dec 2011]

SDF2 Products (1)

mRNA Protein Name
NM_006923.4 NP_008854.2 stromal cell-derived factor 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables misfolded protein binding IMP
IMP: Inferred from mutant phenotype
28597544 GOA
Biological Process GO Annotation Evidence References Source
involved in chaperone cofactor-dependent protein refolding IMP
IMP: Inferred from mutant phenotype
28597544 GOA
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
28597544 GOA
part of protein folding chaperone complex IPI
IPI: Inferred from physical interaction
28597544 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SDF2 Protein Structure

MIR

MIR: MIR domain (41 - 184)

  • 0
  • 100
  • 200
  • 211 a.a.
Protein Preferred Names Protein Names

stromal cell-derived factor 2

  • SDF-2

Recombinant SDF2 Proteins

Cat. No. Product Name Accession Purity
HY-P76054 SDF-2 Protein, Human (sf9, His) Q6IBU4 (S19-L211) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12587 SDF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12588 SDF2L1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21429 Sdf2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27947 Sdf2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus SDF2 MGD MGI:108019
Canis familiaris SDF2 VGNC VGNC:45947
Macaca mulatta SDF2 VGNC VGNC:104649
Rattus norvegicus SDF2 RGD RGD:1307274
Felis catus SDF2 VGNC VGNC:97618
Bos taurus SDF2 VGNC VGNC:34385
Others SDF2 NCBI