2. Gene
  3. ILRUN - inflammation and lipid regulator with UBA-like and NBR1-like domains Gene

ILRUN - inflammation and lipid regulator with UBA-like and NBR1-like domains Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as FP852; C6orf106; dJ391O22.4

Gene ID: 64771 | Gene type: protein coding

About ILRUN

Cytogenetic location: 6p21.31 Genomic coordinates (GRCh38): 6:34,587,288-34,696,767 (from NCBI)

This gene has 3 transcripts (splice variants) and 262 orthologues. Ubiquitous expression in fat (RPKM 19.9), testis (RPKM 15.9) and 25 other tissues.

Summary

This gene encodes a protein with N-terminal ubiquitin-associated (UBA)-like and central neighbor of BRCA1 gene 1 (NBR1)-like domains. The protein acts an inhibitor of Antiviral and proinflammatory cytokine transcription and as a regulator of the renin-angiotensin-aldosterone system (RAAS). [provided by RefSeq, Jul 2021]

ILRUN Products(2)

mRNA Protein Name
NM_022758.6 NP_073595.2 protein ILRUN isoform b
NM_024294.4 NP_077270.1 protein ILRUN isoform a

ILRUN Protein Structure

UBA_4

UBA_4: UBA-like domain (26 - 66)

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  • 298 a.a.
Protein Preferred Names Protein Names

protein ILRUN

inflammation and lipid regulator with UBA-like and NBR1-like domains protein

Related Diseases

Diseases Alias
Meninges Sarcoma

Meningeal Sarcoma

Sarcoma Of Meninges

Meningothelial Sarcoma

Leptomeningeal Sarcoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06789 ILRUN Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ILRUN RGD RGD:1559829
Mus musculus ILRUN MGD MGI:106281
Macaca mulatta ILRUN VGNC VGNC:83428
Bos taurus ILRUN VGNC VGNC:52675
Canis familiaris ILRUN VGNC VGNC:49210
Felis catus ILRUN VGNC VGNC:102443