FNDC4 - fibronectin type III domain containing 4 Gene

Also Known as FRCP1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 64838

About FNDC4

Cytogenetic location: 2p23.3 Genomic coordinates (GRCh38): 2:27,491,883-27,495,200 (from NCBI)

This gene has 3 transcripts (splice variants), 152 orthologues and 1 paralogue. Biased expression in adrenal (RPKM 35.7), brain (RPKM 13.1) and 11 other tissues.

Summary

Involved in response to transforming growth factor beta. Predicted to be located in endoplasmic reticulum and extracellular space. Predicted to be active in extracellular region and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

FNDC4 Products (1)

mRNA Protein Name
NM_022823.3 NP_073734.1 fibronectin type III domain-containing protein 4 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in response to transforming growth factor beta IEP
IEP: Inferred from expression pattern
27066907 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FNDC4 Protein Structure

fn3

fn3: Fibronectin type III domain (48 - 129)

  • 0
  • 100
  • 200
  • 234 a.a.
Protein Preferred Names Protein Names

fibronectin type III domain-containing protein 4

  • fibronectin type III repeat-containing protein 1

Recombinant FNDC4 Proteins

Cat. No. Product Name Accession Purity
HY-P76935 FNDC4 Protein, Human (HEK293, Fc) Q9H6D8/NP_073734.1 (D45-T167) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Colitis
Inflammatory Bowel Disease

  • Inflammatory Bowel Diseases

  • Bowel Disease, Inflammatory
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05021 FNDC4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20021 Fndc4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26524 Fndc4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta FNDC4 VGNC VGNC:72538
Felis catus FNDC4 VGNC VGNC:62321
Rattus norvegicus FNDC4 RGD RGD:6496095
Bos taurus FNDC4 VGNC VGNC:29064
Canis familiaris FNDC4 VGNC VGNC:40930
Mus musculus FNDC4 MGD MGI:1917195
Others FNDC4 NCBI