TRAK2 - trafficking kinesin protein 2 Gene

Also Known as GRIF1; MILT2; OIP98; CALS-C; GRIF-1; ALS2CR3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 66008

About TRAK2

Cytogenetic location: 2q33.1 Genomic coordinates (GRCh38): 2:201,377,207-201,451,458 (from NCBI)

This gene has 5 transcripts (splice variants), 211 orthologues and 2 paralogues. Ubiquitous expression in heart (RPKM 26.1), thyroid (RPKM 23.5) and 25 other tissues.

Summary

Predicted to enable GABA Receptor binding activity and Myosin binding activity. Predicted to be involved in several processes, including mitochondrion distribution; organelle transport along microtubule; and protein targeting. Predicted to be located in cytoplasm and plasma membrane. Predicted to be active in cytoplasmic vesicle; dendrite; and mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

TRAK2 Products (1)

mRNA Protein Name
NM_015049.3 NP_055864.2 trafficking kinesin-binding protein 2

TRAK2 Protein Structure

HAP1_N

HAP1_N: HAP1 N-terminal conserved region (48 - 353)

Milton

Milton: Kinesin associated protein (413 - 567)

Milton

Milton: Kinesin associated protein (700 - 846)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 914 a.a.
Protein Preferred Names Protein Names

trafficking kinesin-binding protein 2

  • O-linked N-acetylglucosamine transferase interacting protein 98

Related Diseases

Diseases Alias
Amyotrophic Lateral Sclerosis 2, Juvenile

  • ALS2

  • Als, Juvenile

  • Alsj

  • Amyotrophic Lateral Sclerosis Type 2

  • Amyotrophic Lateral Sclerosis 2

  • Amyotrophic Lateral Sclerosis Type 2, Juvenile

  • Amyotrophic Lateral Sclerosis Juvenile

  • Amyotrophic Lateral Sclerosis Juvenile 2

  • Sclerosis, Lateral, Amyotrophic, Type Type 2
Spinal Cord Lymphoma

  • Lymphoma Of The Spinal Cord

  • Spinal Cord Cancer

  • Spine Lymphoma

  • Spinal Cord--Cancer
Neuropathy, Congenital Hypomyelinating, 1, Autosomal Recessive

  • Charcot-Marie-Tooth Disease Type 4

  • Charcot-Marie-Tooth Disease Type 4e

  • Hereditary Motor And Sensory Neuropathy

  • Cmt4e

  • CHN1

  • Hypomyelinating Neuropathy, Congenital, 1

  • Charcot-Marie-Tooth Neuropathy Type 4e

  • Neuropathy, Congenital Hypomyelinating, 1

  • Ar-Cmt1

  • Autosomal Recessive Demyelinating Charcot-Marie-Tooth

  • Cmt4

  • Neuropathy, Congenital Hypomyelinating Or Amyelinating, Autosomal Recessive

  • Hypomyelination, Severe Congenital

  • Charcot-Marie-Tooth Disease, Type 4e

  • Charcot-Marie-Tooth Neuropathy, Type 4e

  • Autosomal Recessive Congenital Hypomyelinating Or Amyelinating Neuropathy

  • Autosomal Recessive Congenital Hypomyelinating Neuropathy

  • Congenital Amyelinating Neuropathy

  • Congenital Hypomyelinating Neuropathy Autosomal Recessive

  • Neuropathy, Congenital Hypomyelinating Or Amyelinating

  • Severe Congenital Hypomyelination

  • Hereditary Sensory Motor Neuropathy

  • Charcot-Marie-Tooth Disease, Demyelinating, Autosomal Recessive

  • Neuropathy, Hypomyelinating, Congenital, Type 1

  • Neuropathy, Motor And Sensory, Hereditary

  • Congenital Hypomyelinating Neuropathy

  • Hereditary Motor And Sensory Neuropathies

  • Hereditary Sensorimotor Neuropathy

  • Hmsn - [Hereditary Motor And Sensory Neuropathy]

  • Hsmn - [Hereditary Sensory And Motor Neuropathy]

  • Hereditary Motor And Sensory Neuropathy, Types I-Iv
Hereditary Spastic Paraplegia

  • Familial Spastic Paraplegia

  • Hereditary Spastic Paraparesis

  • Strumpell-Lorrain Disease

  • Familial Spastic Paraparesis

  • Hsp

  • Spg

  • Strümpell-Lorrain Disease

  • Spastic Paraplegia, Hereditary

  • French Settlement Disease

  • Strumpell-Lorrain Syndrome

  • Fsp

  • Spastic Paraplegia, Familial

  • Spastic Paraplegia Hereditary

  • Spastic Paraplegia 3, Autosomal Dominant

  • Spastic Paraparesis

  • Hereditary Spastic Paralysis

  • Familial Spastic Paralysis

  • Hereditary Spastic Ataxia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14980 TRAK2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21794 Trak2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28310 Trak2 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta TRAK2 VGNC VGNC:99413
Bos taurus TRAK2 VGNC VGNC:36281
Felis catus TRAK2 VGNC VGNC:66506
Mus musculus TRAK2 MGD MGI:1918077
Canis familiaris TRAK2 VGNC VGNC:47774
Rattus norvegicus TRAK2 RGD RGD:620915
Others TRAK2 NCBI