Chtop - chromatin target of PRMT1 Gene

Also Known as Fop; Srag; 2500003M10Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66511

Summary

Predicted to enable mRNA binding activity and methyl-CpG binding activity. Acts upstream of or within in utero embryonic development. Predicted to be located in cytoplasmic ribonucleoprotein granule. Predicted to be part of transcription export complex. Predicted to be active in nuclear speck. Is expressed in several structures, including alimentary system; dorsal root ganglion; integumental system; olfactory epithelium; and thymus. Orthologous to human CHTOP (chromatin target of PRMT1). [provided by Alliance of Genome Resources, Apr 2022]

Chtop Products (8)

mRNA Protein Name
NM_001293776.1 NP_001280705.1 chromatin target of PRMT1 protein isoform 1
NM_001293777.1 NP_001280706.1 chromatin target of PRMT1 protein isoform 2
NM_001293778.1 NP_001280707.1 chromatin target of PRMT1 protein isoform 4
NM_001293779.1 NP_001280708.1 chromatin target of PRMT1 protein isoform 5
NM_001293780.1 NP_001280709.1 chromatin target of PRMT1 protein isoform 6
NM_001293781.1 NP_001280710.1 chromatin target of PRMT1 protein isoform 7
NM_001293782.1 NP_001280711.1 chromatin target of PRMT1 protein isoform 3
NM_023215.6 NP_075704.2 chromatin target of PRMT1 protein isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19858291 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
27996060 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chromatin target of PRMT1 protein

  • Friend of PRMT1 protein

  • small arginine- and glycine-rich protein

  • small protein rich in arginine and glycine

Chtop Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Chtop Q9CY57 Prmt5 Mus musculus Q8CIG8
Anti Bait CoIP
19858291
Intra
Chtop Q9CY57 Prmt5 Mus musculus Q8CIG8
Radiolabeled Methyl
19858291
Intra
Chtop Q9CY57 Prmt5 Mus musculus Q8CIG8
Anti Tag CoIP
19858291
Intra
Chtop Q9CY57 Prmt1 Mus musculus Q9JIF0
Anti Tag CoIP
19858291
Intra
Chtop Q9CY57 Prmt1 Mus musculus Q9JIF0
Anti Bait CoIP
19858291
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02697 CHTOP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22441 Chtop Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28964 Chtop Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Chtop NCBI NCBI:26097