Sbds - SBDS ribosome maturation factor Gene

Also Known as SDS; CGI-97; 4733401P19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66711

Summary

This gene encodes a protein that is necessary for ribosome function and maintaining normal levels of protein synthesis. The encoded protein may function to activate ribosomes for translation, and may be involved in cellular response to stress and DNA damage. Loss of this gene is embryonic lethal while deficiency of the encoded protein in the pancreas is associated with symptoms of Shwachman-Diamond syndrome. [provided by RefSeq, Dec 2015]

Sbds Products (1)

mRNA Protein Name
NM_023248.2 NP_075737.1 ribosome maturation protein SBDS

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within inner cell mass cell proliferation IMP
IMP: Inferred from mutant phenotype
16914746 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ribosome maturation protein SBDS

  • SBDS ribosome assembly guanine nucleotide exchange factor

  • Shwachman-Bodian-Diamond syndrome homolog

  • protein 22A3

  • shwachman-Bodian-Diamond syndrome protein homolog

Recombinant Sbds Proteins

Cat. No. Product Name Accession Purity
HY-P76049 SBDS Protein, Mouse (His) P70122 (M1-E250) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-D2939 BGSBD / Unkown
HY-RS12463 SBDS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-168535 SJ6145 / Unkown
HY-181810 EG36 Inhibitor / Unkown
HY-RS18499 Sbds Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24981 Sbds Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sbds NCBI NCBI:51119