Trim35 - tripartite motif-containing 35 Gene

Also Known as NC8; HLS5; Mair; mKIAA1098; 0710005M05Rik; A430106H13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66854

Summary

Predicted to enable ubiquitin protein Ligase activity. Acts upstream of or within negative regulation of cell population proliferation and positive regulation of apoptotic process. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; genitourinary system; lung; and sensory organ. Orthologous to human TRIM35 (tripartite motif containing 35). [provided by Alliance of Genome Resources, Apr 2022]

Trim35 Products (1)

mRNA Protein Name
NM_029979.3 NP_084255.2 E3 ubiquitin-protein ligase TRIM35

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25907537 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of myeloid cell apoptotic process IDA
IDA: Inferred from direct assay
12692137 MGI
acts upstream of or within negative regulation of cell population proliferation IDA
IDA: Inferred from direct assay
14662771 MGI
acts upstream of or within positive regulation of myeloid cell apoptotic process IDA
IDA: Inferred from direct assay
12692137 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
12692137 MGI
located in nucleus IDA
IDA: Inferred from direct assay
14662771 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase TRIM35

  • hemopoietic lineage switch protein 5

  • macrophage-derived apoptosis-inducing RBCC protein

  • protein Nc8

  • tripartite motif-containing protein 35

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-183629 ZNF281-IN-1 / Unkown
HY-RS15039 TRIM35 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21209 Trim35 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27725 Trim35 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trim35 NCBI NCBI:23087