Fgf22 - fibroblast growth factor 22 Gene

Also Known as Fgf5d; FGF-22; 2210414E06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67112

Summary

Predicted to enable Fibroblast Growth Factor receptor binding activity and growth factor activity. Predicted to be involved in several processes, including Fibroblast Growth Factor receptor signaling pathway; positive regulation of cell population proliferation; and positive regulation of macromolecule metabolic process. Located in Golgi apparatus; cell surface; and nucleolus. Is expressed in brain; early conceptus; gonad; and spinal cord. Orthologous to human FGF22 (Fibroblast Growth Factor 22). [provided by Alliance of Genome Resources, Apr 2022]

Fgf22 Products (2)

mRNA Protein Name
NM_001368662.1 NP_001355591.1 fibroblast growth factor 22 isoform 2 precursor
NM_023304.2 NP_075793.1 fibroblast growth factor 22 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15806171 MGI
Biological Process GO Annotation Evidence References Source
involved in regulation of synapse maturation IDA
IDA: Inferred from direct assay
20505669 MGI
involved in regulation of synapse maturation IMP
IMP: Inferred from mutant phenotype
20505669 MGI
involved in trans-synaptic signaling IDA
IDA: Inferred from direct assay
27627962 MGI
involved in trans-synaptic signaling IMP
IMP: Inferred from mutant phenotype
27627962 MGI
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
20505669 MGI
is active in GABA-ergic synapse IMP
IMP: Inferred from mutant phenotype
20505669 MGI
located in Golgi apparatus IDA
IDA: Inferred from direct assay
12837279 MGI
located in cell surface IDA
IDA: Inferred from direct assay
12837279 MGI
NOT located in extracellular region IDA
IDA: Inferred from direct assay
12837279 MGI
is active in extrinsic component of postsynaptic density membrane IDA
IDA: Inferred from direct assay
27627962 MGI
is active in extrinsic component of postsynaptic density membrane IMP
IMP: Inferred from mutant phenotype
27627962 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
20505669 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
20505669 MGI
located in nucleolus IDA
IDA: Inferred from direct assay
12837279 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
20505669 MGI
is active in postsynapse IMP
IMP: Inferred from mutant phenotype
20505669 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fibroblast growth factor 22

  • fibroblast growth factor 5d

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-148432 FGF22-IN-1 Inhibitor 98.07% Unkown
HY-RS04899 FGF22 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174699 Human FGF22 mRNA / Unkown
HY-RS19434 Fgf22 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25925 Fgf22 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fgf22 NCBI NCBI:27006