Rnf149 - ring finger protein 149 Gene

Also Known as Greul4; Gm15832; 1600023E10Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67702

Summary

Enables ubiquitin protein Ligase activity. Acts upstream of or within cellular response to xenobiotic stimulus; negative regulation of MAPK cascade; and regulation of protein stability. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human RNF149 (ring finger protein 149). [provided by Alliance of Genome Resources, Apr 2022]

Rnf149 Products (1)

mRNA Protein Name
NM_001033135.3 NP_001028307.2 E3 ubiquitin-protein ligase RNF149 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22628551 MGI
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
22628551 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to xenobiotic stimulus IDA
IDA: Inferred from direct assay
22628551 MGI
acts upstream of or within negative regulation of MAPK cascade IDA
IDA: Inferred from direct assay
22628551 MGI
acts upstream of or within regulation of protein stability IDA
IDA: Inferred from direct assay
22628551 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase RNF149

  • RING-type E3 ubiquitin transferase RNF149

  • goliath-related E3 ubiquitin-protein ligase 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12057 RNF149 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21188 Rnf149 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27704 Rnf149 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rnf149 NCBI NCBI:284996