SULT1A1 - sulfotransferase family 1A member 1 Gene

Homo sapiens

Also known as PST; STP; STP1; P-PST; ST1A1; ST1A3; TSPST1; ts-PST; P-PST 1; HAST1/HAST2

Gene ID: 6817 | Gene type: protein coding

About SULT1A1

Cytogenetic location: 16p11.2 Genomic coordinates (GRCh38): 16:28,605,258-28,623,375 (from NCBI)

This gene has 5 transcripts (splice variants), 757 orthologues and 12 paralogues. Broad expression in duodenum (RPKM 44.2), liver (RPKM 36.4) and 22 other tissues.

Summary

Sulfotransferase enzymes catalyze the sulfate conjugation of many Hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable Enzyme activity. Multiple alternatively spliced variants that encode two isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

SULT1A1 Products(10)

mRNA	Protein	Name
NM_001055.4	NP_001046.2	sulfotransferase 1A1 isoform a
NM_001394421.1	NP_001381350.1	sulfotransferase 1A1 isoform a
NM_001394422.1	NP_001381351.1	sulfotransferase 1A1 isoform a
NM_001394423.1	NP_001381352.1	sulfotransferase 1A1 isoform a
NM_001394424.1	NP_001381353.1	sulfotransferase 1A1 isoform a
NM_001394425.1	NP_001381354.1	sulfotransferase 1A1 isoform a
NM_177529.3	NP_803565.1	sulfotransferase 1A1 isoform a
NM_177530.4	NP_803566.1	sulfotransferase 1A1 isoform a
NM_177534.4	NP_803878.1	sulfotransferase 1A1 isoform a
NM_177536.5	NP_803880.2	sulfotransferase 1A1 isoform c

SULT1A1 Protein Structure

Sulfotransfer_1

0
100
200
295 a.a.

Protein Preferred Names

Protein Names

sulfotransferase 1A1

aryl sulfotransferase 1

Recombinant SULT1A1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70969	SULT1A1 Protein, Human (His)	AAH00923.1 (M1-L295)	≥95%

Related Diseases

Diseases

Alias

Mandibulofacial Dysostosis With Alopecia

MFDA

Acetaminophen Metabolism

Ceroid Lipofuscinosis, Neuronal, 3

Batten Disease	Juvenile Neuronal Ceroid Lipofuscinosis
Neuronal Ceroid Lipofuscinosis 3	CLN3
Jncl	Spielmeyer-Vogt Disease
Vogt-Spielmeyer Disease	Spielmeyer-Sjogren Disease
Cln3 Disease	Neuronal Ceroid Lipofuscinosis, Juvenile
Cln3 Disease, Juvenile	Spielmeyer Sjogren Disease
Vogt Spielmeyer Disease	Batten-Mayou Disease
Batten-Spielmeyer-Vogt Disease	Cln3-Related Neuronal Ceroid-Lipofuscinosis
Juvenile Batten Disease	Juvenile Cerebroretinal Degeneration
Classic Juvenile Ncl	Classic Juvenile Neuronal Ceroid Lipofuscinosis
Juvenile Ncl	Lipofuscinosis, Ceroid, Neuronal, Type 3

Breast Cancer

Breast Carcinoma	Male Breast Cancer
Breast Cancer, Familial	Malignant Neoplasm Of Breast
Breast Cancer, Susceptibility To	Breast Cancer, Early-Onset
Malignant Tumor Of Breast	Carcinoma Of Male Breast
Breast Cancer, Invasive Ductal	Breast Cancer, Protection Against
Breast Cancer, Somatic	Breast Cancer, Male
Breast Cancer, Lobular, Somatic	Breast Tumor
Mammary Cancer	Mammary Tumor
Malignant Neoplasm Of Male Breast	Mammary Carcinoma
Male Breast Carcinoma	Familial Cancer Of Breast
Invasive Ductal Breast Carcinoma	Breast Cancer Susceptibility
Breast Cancer, Male, Susceptibility To	Breast Cancer, Early-Onset, Susceptibility To
Malignant Tumor Of The Breast	Mammary Neoplasm
Primary Breast Cancer	Neoplasm Of Male Breast
Carcinoma Of Breast	Breast Cancer In Men
Familial Breast Cancer	Cancer Of Breast
BC	Breast Cancer Familial
Breast Cancer Familial Male	Breast Cancer, Familial Male
Breast Male Carcinoma	Breast Neoplasms
Breast Neoplasms, Male	Mammary Tumors
Mammary Carcinomas	Cancer, Breast
Cancer, Breast, Susceptibility	Invasive Breast Ductal Carcinoma
Breast Neoplasm	Susceptibility To Breast Cancer
Mammary Neoplasms	Animal Mammary Neoplasms
Primary Malignant Neoplasm Of Breast	Infiltrating Ductal Carcinoma Of Breast
Infiltrating Duct Carcinoma Of Unspecified Site	Infiltrating Ductular Carcinoma Of Unspecified Site
Invasive Breast Carcinoma Of No Special Type	Microinvasive Carcinoma Of Breast
Carcinoma With Apocrine Differentiation

Endometrial Cancer

Endometrial Carcinoma	Endometrial Neoplasm
Malignant Neoplasm Of Endometrium	Endometrioid Carcinoma
Endometrial Neoplasms	Carcinoma, Endometrioid
Endometrial Cancer, Familial	Endometrial Carcinoma, Somatic
Endometrial Cancer, Susceptibility To	Endometrial Ca
Malignant Endometrial Neoplasm	Neoplasm Of Endometrium
Primary Malignant Neoplasm Of Endometrium	Tumor Of Endometrium
Carcinoma Of The Endometrium	Endometrioid Carcinoma Of Female Reproductive System
ENDMC	Carcinoma Endometrioid
Endometrial Cancers	Cancer, Endometrial
Uterine Corpus Cancer

Colorectal Cancer

Colon Cancer	Colorectal Carcinoma
Colon Carcinoma	Colorectal Cancer, Susceptibility To
Carcinoma Of Colon	CRC
Colorectal Cancer With Chromosomal Instability, Somatic	Colon Cancer, Somatic
Colon Cancer, Susceptibility To	Colonic Neoplasms
Colorectal Neoplasms	Colorectal Cancer, Somatic
Colon Cancer, Advanced, Somatic	Colonic Carcinoma
Colorectal Carcinomas	Colon Cancers
Colorectal Cancers	Cancer, Colorectal, Somatic
Cancer, Colon	Cancer, Colorectal, Susceptibility To
Colorectal Neoplasm	Colonic Neoplasm
Malignant Tumor Of Colon

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS14013	SULT1A1 Human Pre-designed siRNA Set A	/	Unkown
HY-RS14016	SULT1B1 Human Pre-designed siRNA Set A	/	Unkown
HY-RS14019	SULT1E1 Human Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	SULT1A1	RGD	RGD:3767
Mus musculus	SULT1A1	MGD	MGI:102896
Others	SULT1A1	NCBI

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