TMSB4X - thymosin beta 4 X-linked Gene

Homo sapiens

Also known as FX; TB4X; PTMB4; TMSB4

Gene ID: 7114 | Gene type: protein coding

About TMSB4X

Cytogenetic location: Xp22.2 Genomic coordinates (GRCh38): X:12,975,110-12,977,223 (from NCBI)

This gene has 4 transcripts (splice variants), 34 orthologues, 1 paralogue and is associated with 32 phenotypes. Broad expression in spleen (RPKM 3301.5), lymph node (RPKM 3201.4) and 24 other tissues.

Summary

This gene encodes an actin sequestering protein which plays a role in regulation of actin polymerization. The protein is also involved in cell proliferation, migration, and differentiation. This gene escapes X inactivation and has a homolog on chromosome Y. [provided by RefSeq, Jul 2008]

TMSB4X Products(1)

mRNA	Protein	Name
NM_021109.4	NP_066932.1	thymosin beta-4

TMSB4X Protein Structure

Thymosin

0
44 a.a.

Protein Preferred Names

Protein Names

thymosin beta-4

prothymosin beta-4

Recombinant TMSB4X Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71930	TMSB4X Protein, Human	P62328 (S2-S44)	≥95%
HY-P72776	Thymosin beta 4 Protein, Human	P62328 (S2-S44)	≥95%
HY-P71930A	TMSB4X Protein, Human (His)	P62328 (S2-S44)	≥95%

Related Diseases

Diseases

Alias

Osteoarthritis

Osteoarthrosis	Degenerative Joint Disease
Hypertrophic Arthritis	Arthropathy
Degenerative Polyarthritis	Degenerative Arthritis
Osteoarthrosis And Allied Disorder	Arthritis, Degenerative
Oa	Osteoarthritis Deformans
Osteoarthrosis Deformans	Kashin-Beck Disease

Pulmonary Systemic Sclerosis

Lung Disease With Systemic Sclerosis

Lung Involvement In Systemic Sclerosis

Invasive Malignant Thymoma

Infiltrating Thymoma	Thymoma Malignant Invasive
Invasive Thymoma And Thymic Carcinoma

Thymoma

Primary Thymic Epithelial Neoplasm	Primary Thymic Epithelial Tumor
Thymus Neoplasms

Lateral Myocardial Infarction

Fibrosarcoma

Neoplasms, Fibrous Tissue	Fibrocytic Tumor
Fibrosarcoma Of Soft Tissue	Fibrous Tissue Neoplasm

Keratopathy

Colorectal Cancer

Colon Cancer	Colorectal Carcinoma
Colon Carcinoma	Colorectal Cancer, Susceptibility To
Carcinoma Of Colon	CRC
Colorectal Cancer With Chromosomal Instability, Somatic	Colon Cancer, Somatic
Colon Cancer, Susceptibility To	Colonic Neoplasms
Colorectal Neoplasms	Colorectal Cancer, Somatic
Colon Cancer, Advanced, Somatic	Colonic Carcinoma
Colorectal Carcinomas	Colon Cancers
Colorectal Cancers	Cancer, Colorectal, Somatic
Cancer, Colon	Cancer, Colorectal, Susceptibility To
Colorectal Neoplasm	Colonic Neoplasm
Malignant Tumor Of Colon

Malignant Iris Melanoma

Malignant Melanoma Of Iris

Melanoma Of The Iris

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14775	TMSB4X Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	TMSB4X	MGD	MGI:99510
Rattus norvegicus	TMSB4X	RGD	RGD:621622

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