Ddhd2 - DDHD domain containing 2 Gene

Also Known as SAMWD1; mKIAA0725; 2010305K11Rik

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 72108

Summary

Enables triglyceride Lipase activity. Involved in lipid droplet organization and triglyceride catabolic process. Acts upstream of or within positive regulation of mitochondrial fission. Located in membrane. Used to study hereditary spastic paraplegia 54. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 54. Orthologous to human DDHD2 (DDHD domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Ddhd2 Products (2)

mRNA Protein Name
NM_001361595.2 NP_001348524.1 phospholipase DDHD2 isoform 2
NM_028102.2 NP_082378.1 phospholipase DDHD2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables triacylglycerol lipase activity IDA
IDA: Inferred from direct assay
25267624 MGI
enables triacylglycerol lipase activity IMP
IMP: Inferred from mutant phenotype
25267624 MGI
Biological Process GO Annotation Evidence 参考文献 由来
acts upstream of or within lipid droplet organization IMP
IMP: Inferred from mutant phenotype
25267624 MGI
involved in lipid droplet organization IMP
IMP: Inferred from mutant phenotype
25267624 MGI
acts upstream of locomotory behavior IMP
IMP: Inferred from mutant phenotype
25267624 MGI
acts upstream of or within locomotory behavior IMP
IMP: Inferred from mutant phenotype
25267624 MGI
acts upstream of mitochondrial fission IMP
IMP: Inferred from mutant phenotype
24599962 MGI
acts upstream of or within positive regulation of mitochondrial fission IMP
IMP: Inferred from mutant phenotype
24599962 MGI
acts upstream of or within triglyceride catabolic process IMP
IMP: Inferred from mutant phenotype
25267624 MGI
involved in triglyceride catabolic process IMP
IMP: Inferred from mutant phenotype
25267624 MGI
acts upstream of visual learning IMP
IMP: Inferred from mutant phenotype
25267624 MGI
acts upstream of or within visual learning IMP
IMP: Inferred from mutant phenotype
25267624 MGI
Cellular Component GO Annotation Evidence 参考文献 由来
located in membrane IDA
IDA: Inferred from direct assay
25267624 MGI
is active in membrane IMP
IMP: Inferred from mutant phenotype
25267624 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phospholipase DDHD2

  • DDHD domain-containing protein 2

  • SAM, WWE and DDHD domain-containing protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-103060 KLH45 Inhibitor 99.81% Unkown
HY-115671 KLH45b Inhibitor 99.99% Unkown
HY-RS03610 DDHD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20904 Ddhd2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27421 Ddhd2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Ddhd2 NCBI NCBI:23259