Cdkn3 - cyclin-dependent kinase inhibitor 3 Gene

Also Known as KAP; 2410006H10Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72391

Summary

Predicted to enable protein serine/threonine Phosphatase activity and protein tyrosine Phosphatase activity. Predicted to be involved in dephosphorylation. Predicted to act upstream of or within cellular response to DNA damage stimulus and regulation of cell cycle. Predicted to be located in cytosol and perinuclear region of cytoplasm. Predicted to be active in cytoplasm. Is expressed in axial skeleton; cerebral cortex; cranium; hindlimb long bone; and pelvic girdle skeleton. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human CDKN3 (cyclin dependent kinase inhibitor 3). [provided by Alliance of Genome Resources, Apr 2022]

Cdkn3 Products (2)

mRNA Protein Name
NM_001360041.1 NP_001346970.1 cyclin-dependent kinase inhibitor 3 isoform 1
NM_028222.2 NP_082498.1 cyclin-dependent kinase inhibitor 3 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15704002 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cyclin-dependent kinase inhibitor 3

  • CDK2-associated dual-specificity phosphatase

  • kinase-associated phosphatase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02419 CDKN3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20878 Cdkn3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27395 Cdkn3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdkn3 NCBI NCBI:1033