Setd7 - SET domain containing (lysine methyltransferase) 7 Gene

Also Known as KMT7; Set7; H3K4MT; Set7/9; mKIAA1717; 1600028F23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 73251

Summary

Enables protein-lysine N-methyltransferase activity. Involved in protein methylation. Acts upstream of or within heterochromatin organization; peptidyl-lysine methylation; and regulation of histone H3-K9 methylation. Predicted to be located in chromosome and nucleolus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; musculature; and nervous system. Orthologous to human SETD7 (SET domain containing 7, histone lysine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Setd7 Products (1)

mRNA Protein Name
NM_080793.5 NP_542983.3 histone-lysine N-methyltransferase SETD7

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23509280 MGI
enables protein-lysine N-methyltransferase activity IDA
IDA: Inferred from direct assay
23509280 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within chromatin organization IDA
IDA: Inferred from direct assay
23509280 MGI
acts upstream of or within heterochromatin organization IMP
IMP: Inferred from mutant phenotype
23509280 MGI
acts upstream of or within negative regulation of transferase activity IDA
IDA: Inferred from direct assay
23509280 MGI
acts upstream of or within peptidyl-lysine methylation IDA
IDA: Inferred from direct assay
23509280 MGI
involved in peptidyl-lysine methylation IDA
IDA: Inferred from direct assay
35210392 MGI
involved in protein methylation IDA
IDA: Inferred from direct assay
27292644 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

histone-lysine N-methyltransferase SETD7

  • H3-K4 methyltransferase

  • H3-K4-HMTase SETD7

  • SET domain-containing protein 7

  • histone H3-K4 methyltransferase SETD7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-18627A PFI-2 hydrochloride Inhibitor 99.48% Unkown
HY-13807 UNC0646 Inhibitor 99.38% Unkown
HY-18627 PFI-2 Inhibitor 99.68% Unkown
HY-110196 (S)-PFI-2 hydrochloride Inhibitor / Unkown
HY-119164 DC-S238 Inhibitor / Unkown
HY-156455 SETD7-IN-1 Inhibitor / Unkown
HY-182676 DC541 Inhibitor / Unkown
HY-RS12747 SETD7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18842 Setd7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25334 Setd7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Setd7 NCBI NCBI:80854