RELL1 - RELT like 1 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 768211

About RELL1

Cytogenetic location: 4p14 Genomic coordinates (GRCh38): 4:37,586,304-37,686,376 (from NCBI)

This gene has 3 transcripts (splice variants) and 196 orthologues. Ubiquitous expression in stomach (RPKM 7.1), thyroid (RPKM 6.7) and 25 other tissues.

Summary

Involved in positive regulation of p38MAPK cascade. Located in microtubule Cytoskeleton and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

RELL1 Products (2)

mRNA Protein Name
NM_001085399.2 NP_001078868.1 RELT-like protein 1 precursor
NM_001085400.2 NP_001078869.1 RELT-like protein 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22052202 GOA
Biological Process GO Annotation Evidence References Source
involved in positive regulation of p38MAPK cascade IDA
IDA: Inferred from direct assay
28688764 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RELL1 Protein Structure

RELT

RELT: Tumour necrosis factor receptor superfamily member 19 (58 - 102)

  • 0
  • 100
  • 200
  • 271 a.a.
Protein Preferred Names Protein Names

RELT-like protein 1

  • receptor expressed in lymphoid tissues like 1

RELL1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RELL1 Q8IUW5 TREX1 Homo sapiens Q9NSU2-1
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11833 RELL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris RELL1 VGNC VGNC:45468
Rattus norvegicus RELL1 RGD RGD:1307468
Mus musculus RELL1 MGD MGI:2140767
Bos taurus RELL1 VGNC VGNC:33860
Felis catus RELL1 VGNC VGNC:64566
Macaca mulatta RELL1 VGNC VGNC:76846
Others RELL1 NCBI