RETREG2 - reticulophagy regulator family member 2 Gene

Also Known as MAG-2; C2orf17; FAM134A

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79137

Summary

Predicted to enable endoplasmic reticulum-autophagosome adaptor activity. Predicted to be involved in substrate localization to autophagosome. Predicted to act upstream of or within Collagen catabolic process; endoplasmic reticulum organization; and reticulophagy. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in testis (RPKM 39.6), brain (RPKM 29.7) and 25 other tissues.

RETREG2 Products (3)

mRNA Protein Name
NM_001321109.2 NP_001308038.1 reticulophagy regulator 2 isoform 2
NM_001321110.2 NP_001308039.1 reticulophagy regulator 2 isoform 3
NM_024293.6 NP_077269.3 reticulophagy regulator 2 isoform 1
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
21900206 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RETREG2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
RETREG2 Q8NC44 MAP1LC3B Homo sapiens Q9GZQ8 26040720
Cross: Cross-species interaction Intra: Intraspecies interaction