ECHDC3 - enoyl-CoA hydratase domain containing 3 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79746

About ECHDC3

This gene has 5 transcripts (splice variants), 202 orthologues and 13 paralogues. Broad expression in fat (RPKM 46.4), kidney (RPKM 40.8) and 17 other tissues.

Summary

Predicted to enable enoyl-CoA hydratase activity. Involved in positive regulation of cellular response to Insulin stimulus. Predicted to be active in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

ECHDC3 Products (1)

mRNA Protein Name
NM_024693.5 NP_078969.3 enoyl-CoA hydratase domain-containing protein 3, mitochondrial precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in positive regulation of cellular response to insulin stimulus IMP
IMP: Inferred from mutant phenotype
31010960 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ECHDC3 Protein Structure

ECH_1

ECH_1: Enoyl-CoA hydratase/isomerase (54 - 293)

  • 0
  • 100
  • 200
  • 303 a.a.
Protein Preferred Names Protein Names

enoyl-CoA hydratase domain-containing protein 3, mitochondrial

  • enoyl Coenzyme A hydratase domain containing 3

Related Diseases

Diseases Alias
Meningioma, Familial

  • Meningioma

  • Familial Meningioma

  • Meningioma, Familial, Susceptibility To

  • Meningeal Neoplasm

  • Meningeal Neoplasms

  • Meningiomas

  • Meningioma, Nf2-Related, Somatic

  • Meningioma, Sis-Related

  • Meningothelial Cell Tumor

  • Neoplasm Of The Meninges

  • Primary Meningeal Tumor

  • Familial Multiple Meningioma

  • MNGMA

  • Meningioma, Benign, No Icd-O Subtype

  • Intracranial Meningioma

  • Meningothelial Cell Neoplasm

  • Supratentorial Meningioma

  • Primary Neoplasm Of Spinal Meninges

  • Benign Intracranial Meningioma

  • Benign Meningioma

  • Meningeal Tumours

  • Meningeal Sarcoma Of Unspecified Site

  • Meningothelial Sarcoma Of Unspecified Site
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04139 ECHDC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ECHDC3 VGNC VGNC:106040
Rattus norvegicus ECHDC3 RGD RGD:1589147
Felis catus ECHDC3 VGNC VGNC:61709
Bos taurus ECHDC3 VGNC VGNC:28307
Mus musculus ECHDC3 MGD MGI:1915106
Canis familiaris ECHDC3 VGNC VGNC:49790
Others ECHDC3 NCBI