2. Gene
  3. Bmpr1a - bone morphogenetic protein receptor type 1A Gene

Bmpr1a - bone morphogenetic protein receptor type 1A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 81507 | Gene type: protein coding

About Bmpr1a

Primary_assembly 16: 9,736,630-9,780,616 reverse strand.mRatBN7.2:CM026989.1

This gene has 1 transcript (splice variant), 225 orthologues, 11 paralogues and is associated with 20 phenotypes. Biased expression in Heart (RPKM 257.6), Kidney (RPKM 251.6) and 9 other tissues.

Summary

Predicted to enable several functions, including ATP binding activity; Enzyme activator activity; and transmembrane receptor protein serine/threonine kinase activity. Predicted to be involved in several processes, including circulatory system development; positive regulation of cell population proliferation; and positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to act upstream of or within several processes, including animal organ development; limb morphogenesis; and regionalization. Located in dendrite and neuronal cell body. Human ortholog(s) of this gene implicated in hereditary mixed polyposis syndrome 2; intestinal disease; and juvenile polyposis syndrome. Orthologous to human BMPR1A (bone morphogenetic protein receptor type 1A). [provided by Alliance of Genome Resources, Apr 2022]

Bmpr1a Products(1)

mRNA Protein Name
NM_030849.2 NP_110476.1 bone morphogenetic protein receptor type-1A precursor

Bmpr1a Protein Structure

Activin_recp

Activin_recp: pfam01064 (58 - 131)

TGF_beta_GS

TGF_beta_GS: pfam08515 (204 - 231)

STKc_BMPR1a

STKc_BMPR1a: cd14220 (237 - 523)

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  • 532 a.a.
Protein Preferred Names Protein Names

bone morphogenetic protein receptor type-1A

ALK-3

BMP type-1A receptor

BMPR-1A

activin receptor-like kinase 3

bone morphogenetic protein 4 receptor

bone morphogenetic protein receptor, type IA

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01546 BMPR1A Human Pre-designed siRNA Set A / Unkown
HY-RS01547 Bmpr1a Mouse Pre-designed siRNA Set A / Unkown
HY-RS01548 Bmpr1a Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bmpr1a NCBI NCBI:657
Canis familiaris Bmpr1a NCBI NCBI:489077
Mus musculus Bmpr1a NCBI NCBI:12166