Sctr - secretin receptor Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 81779

About Sctr

Primary_assembly 13: 31,127,858-31,180,189 forward strand.mRatBN7.2:CM026986.1

This gene has 3 transcripts (splice variants), 130 orthologues, 42 paralogues and is associated with 1 phenotype. Biased expression in Heart (RPKM 66.8), Spleen (RPKM 27.6) and 6 other tissues.

Summary

Enables peptide binding activity and Secretin Receptor activity. Involved in brain development and positive regulation of cAMP-mediated signaling. Predicted to be located in cytoplasmic microtubule. Predicted to be active in plasma membrane. Orthologous to human SCTR (Secretin Receptor). [provided by Alliance of Genome Resources, Apr 2022]

Sctr Products (1)

mRNA Protein Name
NM_031115.1 NP_112377.1 secretin receptor precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables peptide binding IDA
IDA: Inferred from direct assay
1646711 RGD
enables peptide binding IPI
IPI: Inferred from physical interaction
12403838 RGD
enables secretin receptor activity IDA
IDA: Inferred from direct assay
1646711 RGD
Biological Process GO Annotation Evidence References Source
involved in regulation of cAMP/PKA signal transduction IMP
IMP: Inferred from mutant phenotype
12403838 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Sctr Protein Structure

HormR

HormR: smart00008 (79 - 146)

7tmB1_secretin

7tmB1_secretin: cd15275 (153 - 419)

7tmB1_secretin

7tmB1_secretin: cd15275 (155 - 180)

7tmB1_secretin

7tmB1_secretin: cd15275 (189 - 211)

7tmB1_secretin

7tmB1_secretin: cd15275 (230 - 257)

7tmB1_secretin

7tmB1_secretin: cd15275 (269 - 289)

7tmB1_secretin

7tmB1_secretin: cd15275 (305 - 334)

7tmB1_secretin

7tmB1_secretin: cd15275 (350 - 377)

7tmB1_secretin

7tmB1_secretin: cd15275 (381 - 406)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 464 a.a.
Protein Preferred Names Protein Names

secretin receptor

  • SCT-R

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12568 SCTR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-P11262 GUB021794 Agonist / Unkown
HY-RS12569 Sctr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12570 Sctr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sctr NCBI NCBI:6344