TSPYL5 - TSPY like 5 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 85453

About TSPYL5

Cytogenetic location: 8q22.1 Genomic coordinates (GRCh38): 8:97,273,488-97,277,928 (from NCBI)

This gene has 1 transcript (splice variant), 220 orthologues and 18 paralogues.

Summary

Predicted to enable chromatin binding activity and histone binding activity. Involved in several processes, including cellular response to gamma radiation; positive regulation of protein kinase B signaling; and positive regulation of protein ubiquitination. Predicted to be active in chromatin and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

TSPYL5 Products (1)

mRNA Protein Name
NM_033512.3 NP_277047.2 testis-specific Y-encoded-like protein 5

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21170034 GOA
Biological Process GO Annotation Evidence References Source
involved in cellular response to gamma radiation IMP
IMP: Inferred from mutant phenotype
20079711 GOA
involved in positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
21170034 GOA
involved in positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
20079711 GOA
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: Inferred from mutant phenotype
20079711 GOA
involved in positive regulation of protein ubiquitination IDA
IDA: Inferred from direct assay
21170034 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TSPYL5 Protein Structure

NAP

NAP: Nucleosome assembly protein (NAP) (202 - 382)

  • 0
  • 100
  • 200
  • 300
  • 417 a.a.
Protein Preferred Names Protein Names

testis-specific Y-encoded-like protein 5

  • TSPY-like protein 5

TSPYL5 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TSPYL5 Q86VY4 USP7 Homo sapiens Q93009
Anti Tag CoIP
21170034
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15183 TSPYL5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus TSPYL5 VGNC VGNC:81692
Mus musculus TSPYL5 MGD MGI:2442458
Canis familiaris TSPYL5 VGNC VGNC:54124
Macaca mulatta TSPYL5 VGNC VGNC:104504
Rattus norvegicus TSPYL5 RGD RGD:1311262
Others TSPYL5 NCBI