CD101 - CD101 molecule Gene

Also Known as V7; IGSF2; EWI-101

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9398

About CD101

Cytogenetic location: 1p13.1 Genomic coordinates (GRCh38): 1:117,001,760-117,036,552 (from NCBI)

This gene has 5 transcripts (splice variants), 100 orthologues and 5 paralogues. Broad expression in small intestine (RPKM 2.3), lung (RPKM 2.1) and 18 other tissues.

Summary

Predicted to enable hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides. Predicted to be involved in cell surface receptor signaling pathway. Predicted to act upstream of or within positive regulation of myeloid leukocyte differentiation. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

CD101 Products (4)

mRNA Protein Name
NM_001256106.3 NP_001243035.1 immunoglobulin superfamily member 2 isoform 1 precursor
NM_001256109.3 NP_001243038.1 immunoglobulin superfamily member 2 isoform 1 precursor
NM_001256111.3 NP_001243040.1 immunoglobulin superfamily member 2 isoform 2 precursor
NM_004258.6 NP_004249.2 immunoglobulin superfamily member 2 isoform 1 precursor

CD101 Protein Structure

V-set

V-set: Immunoglobulin V-set domain (23 - 142)

V-set

V-set: Immunoglobulin V-set domain (154 - 252)

Ig_2

Ig_2: Immunoglobulin domain (294 - 380)

I-set

I-set: Immunoglobulin I-set domain (414 - 520)

Ig_2

Ig_2: Immunoglobulin domain (547 - 667)

V-set

V-set: Immunoglobulin V-set domain (686 - 782)

V-set

V-set: Immunoglobulin V-set domain (823 - 912)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1021 a.a.
Protein Preferred Names Protein Names

immunoglobulin superfamily member 2

  • cell surface glycoprotein V7

Related Diseases

Diseases Alias
Langerhans Cell Histiocytosis

  • Histiocytosis X

  • Lch

  • Langerhans Cell Granulomatosis

  • Langerhans-Cell Histiocytosis

  • Letterer-Siwe Disease

  • Hashimoto-Pritzger Disease

  • Histiocytosis, Langerhans-Cell

  • Langerhan'S Cell Histiocytosis

  • Letterer-Siwe Disease Involving Intra-Abdominal Lymph Nodes

  • Letterer-Siwe Disease Involving Intrapelvic Lymph Nodes

  • Letterer-Siwe Disease Involving Intrathoracic Lymph Nodes

  • Letterer-Siwe Disease Involving Lymph Nodes Of Axilla And Upper Limb

  • Letterer-Siwe Disease Involving Lymph Nodes Of Head, Face And Neck

  • Letterer-Siwe Disease Involving Lymph Nodes Of Head, Face, And Neck

  • Letterer-Siwe Disease Involving Lymph Nodes Of Inguinal Region And Lower Limb

  • Letterer-Siwe Disease Involving Lymph Nodes Of Multiple Sites

  • Letterer-Siwe Disease Involving Spleen

  • Letterer-Siwe Disease Of Intra-Abdominal Lymph Nodes

  • Letterer-Siwe Disease Of Intrapelvic Lymph Nodes

  • Letterer-Siwe Disease Of Intrathoracic Lymph Nodes

  • Letterer-Siwe Disease Of Lymph Nodes Of Axilla And Upper Limb

  • Letterer-Siwe Disease Of Lymph Nodes Of Axilla And/Or Upper Limb

  • Letterer-Siwe Disease Of Lymph Nodes Of Head, Face And Neck

  • Letterer-Siwe Disease Of Lymph Nodes Of Head, Face And/Or Neck

  • Letterer-Siwe Disease Of Lymph Nodes Of Inguinal Region Amd/Or Lower Limb

  • Letterer-Siwe Disease Of Lymph Nodes Of Inguinal Region And Lower Limb

  • Letterer-Siwe Disease Of Lymph Nodes Of Inguinal Region And/Or Lower Limb

  • Letterer-Siwe Disease Of Lymph Nodes Of Multiple Sites

  • Letterer-Siwe Disease Of Spleen

  • Familial Letterer-Siwe Disease

  • Langerhans-Cell Histiocytosis Nos
Histiocytosis

  • Chronic Histiocytosis X

  • Hand Schuller Christian Disease

  • Hand-Schüller-Christian Disease

  • Histiocytic Syndrome

  • Histiocytosis, Langerhans-Cell
Median Rhomboid Glossitis

  • Persistent Tuberculum Impar

  • Glossitis Rhomboidea Mediana

  • Superficial Midline Glossitis
Vulvovaginal Candidiasis

  • Candidiasis Of Vulva And Vagina

  • Candidiasis, Vulvovaginal

  • Candidal Vulvovaginitis

  • Candidal: Cervix

  • Monilial Vulvovaginitis

  • Candidiasis Vulvovaginal
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-108009A Rezafungin acetate Inhibitor 99.84% Yes
HY-108009 Rezafungin Inhibitor / Unkown

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02187 CD101 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17459 Cd101 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23916 Cd101 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta CD101 VGNC VGNC:70927
Bos taurus CD101 VGNC VGNC:27001
Rattus norvegicus CD101 RGD RGD:1311453
Canis familiaris CD101 VGNC VGNC:38928
Felis catus CD101 VGNC VGNC:67746
Mus musculus CD101 MGD MGI:2685862
Others CD101 NCBI