PHYHIP - phytanoyl-CoA 2-hydroxylase interacting protein Gene

Also Known as PAHX-AP; PAHXAP1; DYRK1AP3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9796

About PHYHIP

Cytogenetic location: 8p21.3 Genomic coordinates (GRCh38): 8:22,219,703-22,232,099 (from NCBI)

This gene has 5 transcripts (splice variants), 197 orthologues and 1 paralogue. Biased expression in brain (RPKM 50.0), skin (RPKM 16.9) and 4 other tissues.

Summary

Enables protein tyrosine kinase binding activity. Involved in protein localization. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

PHYHIP Products (4)

mRNA Protein Name
NM_001099335.2 NP_001092805.1 phytanoyl-CoA hydroxylase-interacting protein
NM_001363311.2 NP_001350240.1 phytanoyl-CoA hydroxylase-interacting protein
NM_001363312.2 NP_001350241.1 phytanoyl-CoA hydroxylase-interacting protein
NM_014759.5 NP_055574.3 phytanoyl-CoA hydroxylase-interacting protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
enables protein tyrosine kinase binding IPI
IPI: Inferred from physical interaction
15694837 GOA
Biological Process GO Annotation Evidence Verweise Source
involved in protein localization IDA
IDA: Inferred from direct assay
15694837 GOA
Cellular Component GO Annotation Evidence Verweise Source
located in cytoplasm IDA
IDA: Inferred from direct assay
15694837 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phytanoyl-CoA hydroxylase-interacting protein

  • DYRK1A interacting protein 3

Related Diseases

Diseases Alias
Refsum Disease, Classic

  • Refsum Disease

  • Heredopathia Atactica Polyneuritiformis

  • Phytanic Acid Oxidase Deficiency

  • Hmsn Iv

  • Refsum Disease, Adult, 1

  • Refsum'S Disease

  • Phytanic Acid Storage Disease

  • Hereditary Motor And Sensory Neuropathy Iv

  • Hmsn4

  • Hmsn Type Iv

  • Hmsn 4

  • Adult Refsum Disease

  • Classic Refsum Disease

  • Hereditary Motor And Sensory Neuropathy Type Iv

  • Refsum Syndrome

  • Hsmn Iv

  • Disorder Of Cornification 11

  • Doc 11

  • Hereditary Sensory And Motor Neuropathy Type 4

  • Hypertrophic Neuropathy Of Refsum

  • Ard

  • Crd

  • Hereditary Motor And Sensory Neuropathy Type 4

  • Phytanic-Coa Hydroxylase Deficiency

  • RD
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS10459 PHYHIP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta PHYHIP VGNC VGNC:75812
Canis familiaris PHYHIP VGNC VGNC:44512
Felis catus PHYHIP VGNC VGNC:64156
Mus musculus PHYHIP MGD MGI:1860417
Bos taurus PHYHIP VGNC VGNC:32850
Rattus norvegicus PHYHIP RGD RGD:1305790
Others PHYHIP NCBI