Glucocorticoid receptor modulator 4
Glucocorticoid receptor modulator 4 (Compound DL5) is a conjugate of a linker and a glucocorticoid receptor modulator. Glucocorticoid receptor modulator 4 exhibits GRE Reporter activity in mTNF expressing K562 cell with an EC50 of 40 μM. Glucocorticoid receptor modulator 4 binds with an anti-tumor necrosis factor (TNF) antibody, and exhibits anti-inflammtory activity against arthritis in mouse models.
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- CAS No.: 2688785-30-8
- Formula: C37H43BrF3N3O8S
- Molecular Weight:826.72
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
Chemical Information
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CAS No. 2688785-30-8
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Molecular Weight 826.72
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Formula C37H43BrF3N3O8S
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SMILES
O=C(O[C@]1(C(SCF)=O)[C@H](C)C[C@@]2([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)=O)C5=CC=C(F)C(NC([C@@H](NC([C@@H](NC(CBr)=O)C)=O)C)=O)=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Glucocorticoid receptor modulator 4 Related Classifications
HY-163673 Related Classifications
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