Glucodichotomine B
Glucodichotomine B (Compound 13) is a natural product which can be isolated from the roots of Chinese medicinal plant Stellaria dichotoma L. var. lanceolata. Glucodichotomine B shows antitumor activity.
For research use only. We do not sell to patients.
- CAS No.: 845673-16-7
- Formula: C20H22N2O9
- Molecular Weight:434.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Glucodichotomine B (Compound 13) exhibits cytotoxicity towards HCT116 and SMMC7721 cells with IC50 values of 50.29 and 74.52 µm, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 845673-16-7
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Molecular Weight 434.40
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Formula C20H22N2O9
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SMILES
OC[C@@H](C1=C(NC2=CC=CC=C32)C3=CC(C(O)=O)=N1)O[C@@H]([C@@H]([C@H]4O)O)O[C@@H]([C@H]4O)CO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Subcutaneous Cell-Line-Derived Xenograft
Subcutaneous cell-line-derived xenograft (CDX) models are established by implanting cultured human cancer cell lines into immunodeficient mice, where the injected cells form localized tumors that can be monitored in vivo as a measure of tumorigenic potential, growth kinetics, and treatment response. These models are widely used in oncology research because they allow reproducible tumor formation and enable comparative assessment of tumor growth between different cell lines or genetic manipulations in a controlled in vivo microenvironment. Subcutaneous implantation of cancer cells in immunodeficient mice is a standard approach for evaluating tumor growth behavior and therapeutic response across multiple cancer types, including prostate, esophageal, pancreatic, and colon cancer models.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Glucodichotomine B Related Classifications
HY-N10387 Related Classifications
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