GPR40 Activator 3
GPR40 Activator 3 (compound SC) is a potent GPR40 activator. GPR40 Activator 3 mitigates pulmonary fibrosis by inhibiting M2 macrophage polarization via the GPR40/PKD1/CD36 axis.
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- CAS No.: 2980-31-6
- Formule: C14H10O5
- Masse moléculaire:258.23
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
32.52 μM
Compound: 2g
|
Growth inhibition of human HepG2 cells after 24 hrs by MTT assay
Growth inhibition of human HepG2 cells after 24 hrs by MTT assay
|
[PMID: 29609121] |
| MCF7 | IC50 |
>200 μM
Compound: 2g
|
Growth inhibition of human MCF7 cells after 24 hrs by MTT assay
Growth inhibition of human MCF7 cells after 24 hrs by MTT assay
|
[PMID: 29609121] |
| MDA-MB-231 | IC50 |
65.98 μM
Compound: 2g
|
Growth inhibition of human MDA-MB-231 cells after 24 hrs by MTT assay
Growth inhibition of human MDA-MB-231 cells after 24 hrs by MTT assay
|
[PMID: 29609121] |
Chemical Information
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CAS No. 2980-31-6
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Masse moléculaire 258.23
-
Formule C14H10O5
-
SMILES
O=C1C2=C(OC3=C1C(OC)=CC=C3)C=C(O)C=C2O
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Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)