GPX4-IN-17
Based on 1 Customer Validation
GPX4-IN-17 (Compound 9i) is an inhibitor of GPX4 with potent cytotoxicity (IC50 = 0.3 nM). GPX4-IN-17 shows strong binding affinity against GPX4 (KD = 20.4 nM). GPX4-IN-17 inhibits tumor growth in the xenograft tumor mouse model without detectable cytotoxicity. GPX4-IN-17 can enhance cancer chemotherapy and overcome tumor resistance. GPX4-IN-17 can be studied in antitumor reseach.
For research use only. We do not sell to patients.
- Purity: 98.1%
- CAS No.: 3035800-33-7
- Formula: C29H24N4O3S2
- Molecular Weight:540.66
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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GPX4 |
Chemical Information
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CAS No. 3035800-33-7
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Appearance Solid
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Molecular Weight 540.66
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Formula C29H24N4O3S2
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Color Off-white to light yellow
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SMILES
O=C(C1=CSC(C#C)=N1)N(C(C2=CSC3=CC=CC=C32)C(NC(C)(C)C)=O)C4=CC=C(C5=CN=CO5)C=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GPX4-IN-17 Related Classifications
HY-176758 Related Classifications
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