GSK-3β inhibitor 18
GSK-3β inhibitor 18 (compound 2) is a potent inhibitor of GSK-3β, with the IC50 of 0.0021 μM.
For research use only. We do not sell to patients.
- Formula: C25H21N5O4
- Molecular Weight:455.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
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GSK-3β 0.0021 μM (IC50) |
Chemical Information
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Molecular Weight 455.47
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Formula C25H21N5O4
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SMILES
CC1=CN=CN1CCCN(C2=C3C=CC=C2)C=C3C(C(NC4=O)=O)=C4C5=CC=CC=C5[N+]([O-])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)