1. GPCR/G Protein Neuronal Signaling
  2. Adrenergic Receptor
  3. Guanfacine-13C,15N3

Guanfacine-13C,15N3 is the 13C and 15N labeled Guanfacine[1]. Guanfacine is an orally active noradrenergic α2A agonist and has high selective for the α2A receptor subtype. Guanfacine has effects in producing hypotension and sedation. Guanfacine can be used for the research of a variety of prefrontal cortex (PFC) cognitive disorders, including tourette's syndrome and attention deficit hyperactivity disorder (ADHD)[2][3][4].

For research use only. We do not sell to patients.

Guanfacine-<sup>13</sup>C,<sup>15</sup>N<sub>3</sub> Chemical Structure

Guanfacine-13C,15N3 Chemical Structure

CAS No. : 1189924-28-4

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Based on 1 publication(s) in Google Scholar

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Description

Guanfacine-13C,15N3 is the 13C and 15N labeled Guanfacine[1]. Guanfacine is an orally active noradrenergic α2A agonist and has high selective for the α2A receptor subtype. Guanfacine has effects in producing hypotension and sedation. Guanfacine can be used for the research of a variety of prefrontal cortex (PFC) cognitive disorders, including tourette's syndrome and attention deficit hyperactivity disorder (ADHD)[2][3][4].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

250.07

Formula

C813CH9Cl215N3O

CAS No.
Unlabeled CAS

29110-47-2

SMILES

O=C([15NH][13C]([15NH2])=[15NH])CC1=C(Cl)C=CC=C1Cl

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Guanfacine-13C,15N3
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HY-17416AS
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