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Cat. No.: HY-174857

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HBeAg ligand 1

HBeAg ligand 1 (Compound S2) is a HBeAg inhibitor. HBeAg ligand 1 can be used for synthesis of PROTAC HBeAg degrader-1 (HY-174856).

For research use only. We do not sell to patients.

CAS No.: 2361022-13-9
Formula: C₂₅H₂₉ClFN₅O₄S
Molecular Weight:550.05

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

HBeAg ligand 1 Chemical Structure

CAS No.: 2361022-13-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

HBeAg ligand 1 (Compound S2) is a HBeAg inhibitor. HBeAg ligand 1 can be used for synthesis of PROTAC HBeAg degrader-1 (HY-174856)^[1].

Chemical Information

CAS No. 2361022-13-9
Molecular Weight 550.05
Formula C₂₅H₂₉ClFN₅O₄S
SMILES

O=C(C1=C(CN2CCN(C(OC(C)(C)C)=O)CC2)NC(C3=NC=CS3)=N[C@H]1C4=CC=C(F)C=C4Cl)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hales LT, et al. VHL-independent degradation of hepatitis B virus e antigen (HBeAg) by VHL-binding chimeric small molecules. RSC Med Chem. 2025 Mar 28. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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