HIV-1 protease-IN-10
HIV-1 protease-IN-10 (Compound 2) has HIV-1 latency reversing activity (IC50: 0.22 μM). HIV-1 protease-IN-10 binds to the PKCδ C1b domain (IC50: 0.69 μM). HIV-1 protease-IN-10 has stability against esterase-mediated hydrolysis.
For research use only. We do not sell to patients.
- CAS No.: 2982527-11-5
- Formula: C23H40O5
- Molecular Weight:396.56
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Jurkat | CC50 |
>10 μM
Compound: 2
|
Cytotoxicity against human Jurkat cells assessed as reduction in cell viability incubated for 24 hrs by Ghost dye 780 staining based flow cytometric analysis
Cytotoxicity against human Jurkat cells assessed as reduction in cell viability incubated for 24 hrs by Ghost dye 780 staining based flow cytometric analysis
|
[PMID: 37224601] |
Chemical Information
-
CAS No. 2982527-11-5
-
Molecular Weight 396.56
-
Formula C23H40O5
-
SMILES
O=C1OC(CO)(COC(C(CCCCCC)CCCCCC)=O)C/C1=C(C)/C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)