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Cat. No.: HY-146804

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HIV-1 protease-IN-3

HIV-1 protease-IN-3 (compound 14) is a potent inhibitor of HIV-1 protease (IC₅₀=71 nM; EC₅₀=0.86 μM).

For research use only. We do not sell to patients.

Formula: C₂₇H₃₇NO₇S
Molecular Weight:519.65

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

HIV-1 protease-IN-3 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

HIV-1 protease-IN-3 (compound 14) is a potent inhibitor of HIV-1 protease (IC₅₀=71 nM; EC₅₀=0.86 μM)^[1].

All HIV Isoforms :

Chemical Information

Molecular Weight 519.65
Formula C₂₇H₃₇NO₇S
SMILES

O=C1[C@@](C2=CC=C(S(C)(=O)=O)C=C2O[C@@H](C)CO)(CCC(C)C)[C@@H](O)CN1CC3=CC=C(OC)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kojima E, et al. Pocket-to-Lead: Structure-Based De Novo Design of Novel Non-peptidic HIV-1 Protease Inhibitors Using the Ligand Binding Pocket as a Template. J Med Chem. 2022 Apr 28;65(8):6157-6170. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Amount: USD 0.00

Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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HIV-1 protease-IN-3

All HIV Isoforms