Lactivicin
Lactivicin is a non-beta-lactam antibiotic showing beta-lactam action through binding to penicillin-binding protein (PBP). Lactivicin is moderately active against a wide range of Gram-negative bacteria and highly active against Gram-positive bacteria.
For research use only. We do not sell to patients.
- CAS No.: 107167-31-7
- Formula: C10H12N2O7
- Molecular Weight:272.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
Lactivicin (100-1000 μg/mL) is highly susceptible to cephalosporinases and hydrolysed by multiple penicillinases, with full stability only against Bacillus cereus penicillinase[2].
Lactivicin (0.5-10× MIC) lyses E. coli LD-2 cells and induces spheroplasts at 1× MIC, while causing growth stasis at concentrations above 5× MIC[2].
Lactivicin (0.5-10× MIC) exhibits dose-dependent lytic activity against B. subtilis PCI 219, inducing filamentous cells at 1× MIC and strong lysis at concentrations above 5× MIC[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 107167-31-7
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Molecular Weight 272.21
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Formula C10H12N2O7
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SMILES
O=C(O)C(N1OC[C@@H](C1=O)NC(C)=O)(O2)CCC2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)