Hydroquinidine hydrochloride
Hydroquinidine hydrochloride is a potent ion channel blocker, which exhibits strong anti-cancer activity on colon, pancreatic, and hepatocellular cancer cells. Hydroquinidine hydrochloride prolongs the QT interval and has antiarrhythmic efficacy.
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- CAS No.: 1476-98-8
- Formule: C20H27ClN2O2
- Masse moléculaire:362.90
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Chemical Information
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CAS No. 1476-98-8
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Masse moléculaire 362.90
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Formule C20H27ClN2O2
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SMILES
O[C@@H](C1=C(C=C(OC)C=C2)C2=NC=C1)[C@@]3([H])C[C@@]4([H])[C@H](CC)C[N@@]3CC4.Cl
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Yavuz M, et al. A potent ion channel blocker, hydroquinidine, exhibits strong anti-cancer activity on colon, pancreatic, and hepatocellular cancer cells. Mol Biol Rep. 2023 Mar;50(3):2611-2621. [Content Brief]
[2]. Mazzanti A, et al. Hydroquinidine Prevents Life-Threatening Arrhythmic Events in Patients With Short QT Syndrome. J Am Coll Cardiol. 2017 Dec 19;70(24):3010-3015. [Content Brief]
[3]. Chimienti M, et al. Comparison of the effectiveness of dihydroquinidine and quinidine on ventricular ectopy after acute and chronic administration. Cardiovasc Drugs Ther. 1988 Dec;2(5):679-86. [Content Brief]
[4]. Hermida JS, et al. Hydroquinidine therapy in Brugada syndrome. J Am Coll Cardiol. 2004 May 19;43(10):1853-60. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Hydroquinidine hydrochloride Related Classifications
HY-W009065 Related Classifications
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