Hypelodin A
Hypelodin A is a Hypelodin. Hypelodin A can be isolated from H. beanii. Hypelodin A can be used in research on colorectal cancer, breast cancer, and liver cancer.
For research use only. We do not sell to patients.
- CAS No.: 1802181-07-2
- Formula: C38H48O4
- Molecular Weight:568.80
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Hypelodin A (24 h) is used to evaluate the cytotoxicity against HCT 116 cells, HT-29 cells, MDA-MB-231 cells, and HepG2 cells, with IC50 values ranging from 21.8 to >50 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
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Cell Line:HCT 116 cells, HT-29 cells, MDA-MB-231 cells, and HepG2 cells
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Concentration:Various concentrations
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Incubation Time:24 h
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Result:Exhibited IC50 values of 21.8 μM, 23.71 μM, 47.91 μM, and >50 μM against HCT 116, HT-29, MDA-MB-231, and HepG2 cells, respectively.
Chemical Information
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CAS No. 1802181-07-2
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Molecular Weight 568.80
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Formula C38H48O4
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SMILES
C(C=C(C)C)[C@]12C(=C(CC=C(C)C)C(O)=C(C(=O)C3=CC=CC=C3)C1=O)O[C@](/C=C/C=C(C)C)(C)[C@H](CC=C(C)C)C2
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Liver Cancer Modeling
Liver cancer can be classified into primary liver cancer and secondary liver cancer. Secondary liver cancer is the metastatic liver cancer. Primary liver cancer includes hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC) and fibrolamellar HCC, of which HCC is the most common form, accounting for approximately 90% of primary liver cancers[1]. HCC mouse models include chemical agent-induced models, transplanted tumor models, and genetic engineered models.
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Breast Cancer Modeling
Breast cancer is a heterogeneous cancer, and it has been distinguished into four subtypes: luminal A, luminal B, HER2-positive and basal-like. Molecular mutations, epigenetic alterations, hormone exposure and immune microenvironment are related to the progression of breast cancer.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Hypelodin A Related Classifications
HY-N21702 Related Classifications
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