Lvguidingan
Based on 1 Customer Validation
Lvguidingan is a potent anticonvulsant agent. Lvguidingan also has sedative-hypnotic, tranquilizing, and muscle-relaxing actions. Lvguidingan can be used as antiepileptic agent.
For research use only. We do not sell to patients.
- Purity: 99.48%
- CAS No.: 82351-05-1
- Formula: C13H15Cl2NO
- Molecular Weight:272.17
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 82351-05-1
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Appearance Solid
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Molecular Weight 272.17
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Formula C13H15Cl2NO
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Color White to off-white
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SMILES
O=C(NC(C)CC)/C=C/C1=CC=C(Cl)C(Cl)=C1
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Synonyms
Anticonvulsant 7903
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 125 mg/mL (459.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: 2.08 mg/mL (7.64 mM); Suspended solution; Need ultrasonic
This protocol yields a suspended solution of 2.08 mg/mL. Suspended solution can be used for oral and intraperitoneal injection.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Cao LG, Pei YQ. [Analysis of the mechanism of anticonvulsant action of 3, 4-dichlorophenyl propenyl isobutylamide (7903)]. Yao Xue Xue Bao. 1982 Dec;17(12):889-93. [Content Brief]
[2]. Pei YQ. A review of pharmacology and clinical use of piperine and its derivatives. Epilepsia. 1983 Apr;24(2):177-82. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6742 mL | 18.3709 mL | 36.7417 mL | 91.8544 mL |
| 5 mM | 0.7348 mL | 3.6742 mL | 7.3483 mL | 18.3709 mL | |
| 10 mM | 0.3674 mL | 1.8371 mL | 3.6742 mL | 9.1854 mL | |
| 15 mM | 0.2449 mL | 1.2247 mL | 2.4494 mL | 6.1236 mL | |
| 20 mM | 0.1837 mL | 0.9185 mL | 1.8371 mL | 4.5927 mL | |
| 25 mM | 0.1470 mL | 0.7348 mL | 1.4697 mL | 3.6742 mL | |
| 30 mM | 0.1225 mL | 0.6124 mL | 1.2247 mL | 3.0618 mL | |
| 40 mM | 0.0919 mL | 0.4593 mL | 0.9185 mL | 2.2964 mL | |
| 50 mM | 0.0735 mL | 0.3674 mL | 0.7348 mL | 1.8371 mL | |
| 60 mM | 0.0612 mL | 0.3062 mL | 0.6124 mL | 1.5309 mL | |
| 80 mM | 0.0459 mL | 0.2296 mL | 0.4593 mL | 1.1482 mL | |
| 100 mM | 0.0367 mL | 0.1837 mL | 0.3674 mL | 0.9185 mL |
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