1. Terpenoids and Glycosides
  2. Ilexhainanoside D

Ilexhainanoside D 

Cat. No.: HY-N5040
Handling Instructions

Ilexhainanoside D is the main triterpenoid saponin extracted from Ilex hainanensis Merr., and the combination of Ilexhainanoside D and ilexsaponin A1 has anti-inflammation effect.

For research use only. We do not sell to patients.

Ilexhainanoside D Chemical Structure

Ilexhainanoside D Chemical Structure

CAS No. : 1137648-52-2

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Description

Ilexhainanoside D is the main triterpenoid saponin extracted from Ilex hainanensis Merr., and the combination of Ilexhainanoside D and ilexsaponin A1 has anti-inflammation effect[1].

In Vivo

The combination of Ilexhainanoside D and Ilexsaponin A (60, 120 or 240 mg/kg; for 8 weeks) treatment significantly reduces the severity of non-alcoholic fatty liver disease (NAFLD) induced by high-fat diet in a dose-dependent manner. The combination of Ilexhainanoside D and Ilexsaponin A treatment decreases the ratio of Firmicutes/Bacteroidetes, reduces the relative abundance of Desulfovibrio and increases the relative abundance of Akkermansia. The intestinal barrier is improved as evidenced by the upregulation of the expression of zonula occludens-1 (ZO-1) and occludin in the ileum. The combination of Ilexhainanoside D and Ilexsaponin A treatment reduces the entry of LPS into the circulation and decreases the hepatic gene expression levels of proinflammatory cytokines[1].

Molecular Weight

664.82

Formula

C₃₆H₅₆O₁₁

CAS No.

1137648-52-2

SMILES
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Ilexhainanoside DOthersInhibitorinhibitorinhibit

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Ilexhainanoside D
Cat. No.:
HY-N5040
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