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Cat. No.: HY-187121

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Indole-3-aldehyde azine

Indole-3-aldehyde azine is an indole-derived azine compound with no obvious cytotoxicity or antiviral activity.

For research use only. We do not sell to patients.

CAS No.: 1233-49-4
Formula: C₁₈H₁₄N₄
Molecular Weight:286.33

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (281 KB)

Indole-3-aldehyde azine Chemical Structure

CAS No.: 1233-49-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Indole-3-aldehyde azine is an indole-derived azine compound with no obvious cytotoxicity or antiviral activity^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
MT4	CC₅₀	>100 μM	Cytotoxicity against human MT-4 cells assessed as cell viability incubated for 96 hrs by MTT assay. Cytotoxicity against human MT-4 cells assessed as cell viability incubated for 96 hrs by MTT assay.	26077842
MDCK	CC₅₀	>100 μM	Cytotoxicity against canine MDCK cells assessed as cell viability incubated for 72 hrs by MTT assay. Cytotoxicity against canine MDCK cells assessed as cell viability incubated for 72 hrs by MTT assay.	26077842
BHK-21	CC₅₀	>100 μM	Cytotoxicity against hamster BHK-21 cells assessed as cell viability incubated for 72 hrs by MTT assay. Cytotoxicity against hamster BHK-21 cells assessed as cell viability incubated for 72 hrs by MTT assay.	26077842
Vero 76	CC₅₀	≥100 μM	Cytotoxicity against monkey Vero76 cells assessed as cell viability incubated for 72 hrs by MTT assay. Cytotoxicity against monkey Vero76 cells assessed as cell viability incubated for 72 hrs by MTT assay.	26077842

In Vitro

OthersViral Infection

Others

Indole-3-aldehyde azine (compound 13) shows no cytotoxicity against MT-4, MDCK, MDBK, BHK-21 and Vero76 cell lines at concentrations >100 μM (≥100 μM for Vero76), with a CC₅₀ value of >100 μM (≥100 μM for Vero76)^[1].

Viral Infection

Indole-3-aldehyde azine shows no significant antiviral activity against various viruses including HIV-1, H1N1 and Reo-1^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS No. 1233-49-4
Molecular Weight 286.33
Formula C₁₈H₁₄N₄
SMILES

C1(/C=N/N=C/C2=CNC3=C2C=CC=C3)=CNC4=C1C=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (281 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Caneva C, et al. Synthesis and biological evaluation of (acyl)hydrazones and thiosemicarbazones obtained via in situ condensation of iminium salts with nitrogen-containing nucleophiles. Molecular diversity. 2015 Nov;19(4):669-84. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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