Nervous System Disease Models

Capsaicin Customized Diet-2 is a diet containing capsaicin, with the substrate being a maintenance diet at a concentration of 100 ppm. Capsaicin Customized Diet-2 can be used to study the effects of capsaicin on animal organisms. Capsaicin Customized Diet-2 does not include a control diet and is recommended for use in conjunction with the control diet, Standard Chow Diet (Maintenance Diet) (HY-AF0007).

Cuprizone in Maintenance Diet (2000 ppm) (Cuprizone in Maintenance Diet (0.2% w/w)) is a diet containing Cuprizone (HY-W115718) as a maintenance feed, with a Cuprizone concentration of 2000 ppm. Cuprizone in Maintenance Diet (2000 ppm) can be used to study the effects of Cuprizone on animal organisms. Cuprizone in Maintenance Diet (2000 ppm) does not include a control group and is recommended for use in conjunction with the control group, Standard Chow Diet (Maintenance Diet) (HY-AF0007).

Oxotremorine is an agonist for mAChR, that activates M1 and M3 acetylcholine receptors. Oxotremorine exhibits nicotine-like effects in drug discrimination experiments in macaques.

Bicuculline methobromide is a selective GABAA Receptor antagonist with an IC₅₀ value of 3 μM. Bicuculline methobromide induces clonic tonic convulsions in mammals and can also be used to block Ca²⁺ activated potassium channels. Bicuculline methobromide can be used in studies of epilepsy and other related psychiatric disorders.