Inositol nicotinate
Based on 1 Customer Validation
Inositol nicotinate (Hexanicit) has vasodilating effects and can be used in research on peripheral arterial disease, showing efficacy when taken orally. Inositol nicotinate does not significantly improve triglyceride levels in mice induced by biphenyl esters.
For research use only. We do not sell to patients.
- Purity: 98.05%
- CAS No.: 6556-11-2
- Formula: C42H30N6O12
- Molecular Weight:810.72
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Bifendate-treated mice[1]
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Dosage:0.1, 0.3 g/kg; daily; 4 days
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Administration:Oral
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Result:Reduced the level of serum TG slightly, but the difference was not statistically significant.
Chemical Information
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CAS No. 6556-11-2
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Appearance Solid
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Molecular Weight 810.72
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Formula C42H30N6O12
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Color White to off-white
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SMILES
O=C(C1=CC=CN=C1)O[C@H]2[C@@H](OC(C3=CC=CN=C3)=O)[C@@H](OC(C4=CC=CN=C4)=O)[C@H](OC(C5=CC=CN=C5)=O)[C@@H](OC(C6=CC=CN=C6)=O)[C@@H]2OC(C7=CC=CN=C7)=O
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Synonyms
Inositol niacinate; Hexanicit
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
5% TFA in Water : 25 mg/mL (30.84 mM; Need ultrasonic)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (284 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Si-Yuan Pan, et al.High doses of bifendate elevate serum and hepatic triglyceride levels in rabbits and mice: animal models of acute hypertriglyceridemia. Acta Pharmacol Sin. 2006 Jun;27(6):673-8. [Content Brief]
[2]. H Squires, et al. A systematic review and economic evaluation of cilostazol, naftidrofuryl oxalate, pentoxifylline and inositol nicotinate for the treatment of intermittent claudication in people with peripheral arterial disease. NIHR Health Technology Assessment programme: Executive Summaries. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| 5% TFA in Water | 1 mM | 1.2335 mL | 6.1674 mL | 12.3347 mL | 30.8368 mL |
| 5 mM | 0.2467 mL | 1.2335 mL | 2.4669 mL | 6.1674 mL | |
| 10 mM | 0.1233 mL | 0.6167 mL | 1.2335 mL | 3.0837 mL | |
| 15 mM | 0.0822 mL | 0.4112 mL | 0.8223 mL | 2.0558 mL | |
| 20 mM | 0.0617 mL | 0.3084 mL | 0.6167 mL | 1.5418 mL | |
| 25 mM | 0.0493 mL | 0.2467 mL | 0.4934 mL | 1.2335 mL | |
| 30 mM | 0.0411 mL | 0.2056 mL | 0.4112 mL | 1.0279 mL |
Inositol nicotinate Related Classifications
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