Iso cephalomannine
Based on 1 Customer Validation
Iso cephalomannine is a tubulin-targeting cytotoxic agent. Iso cephalomannine induces cytotoxicity in breast cancer cells. Iso cephalomannine can be used in breast cancer-related research.
For research use only. We do not sell to patients.
- CAS No.: 173101-54-7
- Formula: C45H53NO14
- Molecular Weight:831.90
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Iso cephalomannine (compound 1d) exhibits reduced tubulin-binding activity in cell-free microtubule assembly assays, with an ED50 ratio of 1.1 relative to Paclitaxel (HY-B0015)[1].
Iso cephalomannine exhibits low cytotoxicity against human breast cancer MCF7 cells, with an ED50 ratio of 12 relative to Paclitaxel (HY-B0015)[1].
Iso cephalomannine shows no detectable cytotoxicity against MCF7-R drug-resistant human breast cancer cells, with an ED50 greater than 5000 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 173101-54-7
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Molecular Weight 831.90
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Formula C45H53NO14
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SMILES
CC(O[C@]12[C@@]3([H])[C@@H]([C@]4(C(C)(C([C@H](C([C@@]3([C@H](C[C@@]1([H])OC2)O)C)=O)OC(C)=O)=C([C@H](C4)OC([C@H](O)[C@H](C5=CC=CC=C5)NC(C6=CC=CC=C6)=O)=O)C)C)O)OC(/C(C)=C/C)=O)=O
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)