Defoslimod
Defoslimod (OM 174) is an agonist for TLR4 receptor and acts as an immunomodulator. Defoslimod activates macrophages and dendritic cells, induces cytokines secretion, and exhibits antitumor efficacy in rats.
For research use only. We do not sell to patients.
- CAS No.: 171092-39-0
- Formula: C52H100N2O20P2
- Molecular Weight:1135.30
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Macrophage | EC50 |
0.025 μg/mL
Compound: OM-174
|
Induction of NO production in murine macrophage
Induction of NO production in murine macrophage
|
[PMID: 17004714] |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
CAS No. 171092-39-0
-
Molecular Weight 1135.30
-
Formula C52H100N2O20P2
-
SMILES
O=P(O)(O)O[C@H]([C@@H]([C@H]([C@@H]1O)O)NC(C[C@H](O)CCCCCCCCCCC)=O)O[C@@H]1CO[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)OP(O)(O)=O)O)NC(C[C@@H](CCCCCCCCCCC)OC(CCCCCCCCCCC)=O)=O
-
Synonyms
OM 174
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Defoslimod Related Classifications
HY-164386 Related Classifications
Powered by Bioz