Tprn - taperin Gene

Also Known as C430004E15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 97031

Summary

Predicted to enable Phosphatase binding activity. Involved in sensory perception of sound and stereocilium maintenance. Acts upstream of or within auditory receptor cell stereocilium organization. Located in stereocilium base. Is expressed in several structures, including central nervous system; immune system; reproductive system; respiratory system; and submandibular gland. Used to study autosomal recessive nonsyndromic deafness 79. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 79. Orthologous to human TPRN (taperin). [provided by Alliance of Genome Resources, Apr 2022]

Tprn Products (1)

mRNA Protein Name
NM_175286.4 NP_780495.2 taperin

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables actin binding IPI
IPI: Inferred from physical interaction
37952086 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
30380417 MGI
enables protein phosphatase binding IPI
IPI: Inferred from physical interaction
37952086 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within auditory receptor cell stereocilium organization IGI
IGI: Inferred from genetic interaction
30380417 MGI
acts upstream of or within sensory perception of sound IMP
IMP: Inferred from mutant phenotype
30380417 MGI
involved in sensory perception of sound IMP
IMP: Inferred from mutant phenotype
27693694 MGI
involved in stereocilium maintenance IMP
IMP: Inferred from mutant phenotype
27693694 MGI
Cellular Component GO Annotation Evidence References Source
located in microvillus IDA
IDA: Inferred from direct assay
24285636 MGI
located in stereocilium IDA
IDA: Inferred from direct assay
20170899 MGI
located in stereocilium base IDA
IDA: Inferred from direct assay
24285636 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

taperin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14950 TPRN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19645 Tprn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26138 Tprn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tprn NCBI NCBI:286262