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Cat. No.: HY-100885A

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(S)-Acelarin

(Synonyms: (S)-NUC-1031; Fosgemcitabine palabenamide)

(S)-Acelarin ((S)-NUC-1031) is an anti-cancer agent. (S)-Acelarin inhibits the growth of various cancer cells. (S)-Acelarin can be used for the study of solid tumors (e.g., pancreatic cancer, BTC, ovarian cancer) and hematological malignancies.

For research use only. We do not sell to patients.

CAS No.: 1562406-27-2
Formula: C₂₅H₂₇F₂N₄O₈P
Molecular Weight:580.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

(S)-Acelarin Chemical Structure

CAS No.: 1562406-27-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 1562406-27-2
Molecular Weight 580.47
Formula C₂₅H₂₇F₂N₄O₈P
SMILES

FC1([C@H](N2C(N=C(C=C2)N)=O)O[C@@H]([C@H]1O)CO[P@](OC3=CC=CC=C3)(N[C@@H](C)C(OCC4=CC=CC=C4)=O)=O)F
Synonyms

(S)-NUC-1031; Fosgemcitabine palabenamide
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Slusarczyk M, et al. Single Diastereomers of the Clinical Anticancer ProTide Agents NUC-1031 and NUC-3373 Preferentially Target Cancer Stem Cells In Vitro. J Med Chem. 2021 Jun 24;64(12):8179-8193. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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